HitPredict

Interactor 1: ACTY (P42025)
Beta-centractin (Actin-related protein 1B) (ARP1B)
Gene: ACTR1B

Interactor 2: DCTN4 (Q9UJW0)
Dynactin subunit 4 (Dyn4) (Dynactin subunit p62)
Gene: DCTN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	26186194, 28514442, 33961781, 28718761
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Dynactin_p62
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0005869 - dynactin complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 460
+	Hs
		897150 ACTZ_HUMAN (1-376): 0: 728: 90.43		DCTN4_HUMAN (1-460): 0: 767: 100.00
+	Hs
		892100 ACTB_HUMAN (8-376): 0: 581: 53.62		DCTN4_HUMAN (1-460): 0: 767: 100.00
+	Hs
		930046 ACTG_HUMAN (7-376): 0: 581: 53.74		DCTN4_HUMAN (1-460): 0: 767: 100.00
+	Hs
		932440 ACTC_HUMAN (5-376): 0: 577: 53.72		DCTN4_HUMAN (1-460): 0: 767: 100.00
+	Dm
		800134 ACTZ_DROME (1-376): 0: 641: 77.13		Q7K130_DROME (3-427): 0: 532: 36.02