Interactor 1: CRX (O43186)
Cone-rod homeobox protein
Gene: CRX
Interactor 2: ISL2 (Q96A47)
Insulin gene enhancer protein ISL-2 (Islet-2)
Gene: ISL2
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 38297188 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Homeodomain~Homeodomain |
| Common GO terms | GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II GO:1990837 - sequence-specific double-stranded DNA binding |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
