HitPredict

Interactor 1: EFS (O43281)
Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)
Gene: EFS

Interactor 2: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9748319
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0017124 - SH3 domain binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 561 Hs			1 780
+	Hs
		1050792 CASL_HUMAN (6-336): 1.95e-31: 131: 24.93		PTN12_HUMAN (1-780): 0: 573: 100.00
+	Hs
		1050783 ACK1_HUMAN (9-484): 7.38e-24: 108: 14.85		PTN12_HUMAN (1-780): 0: 573: 100.00
+	Hs
		1050826 CASS4_HUMAN (379-557): 1.44e-20: 97.8: 19.89		PTN12_HUMAN (1-780): 0: 573: 100.00
+	Hs
		942572 BCAR1_HUMAN (7-431): 3.42e-12: 71.3: 21.40		PTN12_HUMAN (1-780): 0: 573: 100.00
+	Mm
		777188 BCAR1_MOUSE (7-431): 9.64e-11: 66.6: 19.17		PTN12_MOUSE (1-780): 0: 551: 82.84
+	Hs
		471740 ACK1_HUMAN (9-484): 7.38e-24: 108: 14.85		PTPRC_HUMAN (13-677): 6.94e-141: 449: 19.62
+	Hs
		1053663 CASL_HUMAN (6-336): 1.95e-31: 131: 24.93		PTN11_HUMAN (7-359): 5.77e-124: 385: 29.65
+	Hs
		611057 BCAR1_HUMAN (7-431): 3.42e-12: 71.3: 21.40		PTN1_HUMAN (27-414): 3.72e-126: 385: 25.30
+	Hs
		942575 BCAR1_HUMAN (7-431): 3.42e-12: 71.3: 21.40		PTN11_HUMAN (7-359): 5.77e-124: 385: 29.65
+	Rn
		835035 BCAR1_RAT (6-431): 6.07e-12: 70.5: 20.23		PTN11_RAT (7-359): 1.47e-123: 384: 29.65
+	Hs
		1144635 MINK1_HUMAN (48-378): 4.38e-26: 115: 14.67		PTPRK_HUMAN (17-293): 1.38e-59: 221: 26.67
+	Hs
		1060771 ACK1_HUMAN (9-484): 7.38e-24: 108: 14.85		PTPRJ_HUMAN (49-297): 6.26e-46: 179: 39.13