HitPredict

Interactor 1: FRS3 (O43559)
Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2)
Gene: FRS3

Interactor 2: SH2B1 (Q9NRF2)
SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B)
Gene: SH2B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 25814554, unassigned1126
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRS~PH
Common GO terms GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 492
Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025