HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: SHKB1 (Q8TBC3)
SH3KBP1-binding protein 1 (SETA-binding protein 1)
Gene: SHKBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 707
+	Hs
		987789 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		SHKB1_HUMAN (1-707): 0: 1176: 100.00
+	Hs
		222018 NCK2_HUMAN (1-380): 3.54e-95: 290: 100.00		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45
+	Hs
		593909 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45
+	Mm
		237078 NCK2_MOUSE (1-380): 5.85e-94: 287: 96.05		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Hs
		222146 NCK2_HUMAN (1-380): 3.54e-95: 290: 100.00		KCD17_HUMAN (19-118): 1.59e-34: 135: 45.10
+	Hs
		463692 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		KCNB2_HUMAN (5-232): 3.48e-54: 202: 16.06
+	Hs
		1432564 ITSN2_HUMAN (5-273): 6.53e-36: 141: 19.27		BACD3_HUMAN (1-150): 4.62e-38: 145: 28.29
+	Hs
		987832 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		KCNB2_HUMAN (5-232): 3.48e-54: 202: 16.06
+	Hs
		557308 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		KCNB1_HUMAN (2-232): 7.94e-52: 195: 16.27
+	Hs
		440364 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45
+	Hs
		440342 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		KCNA2_HUMAN (1-231): 1.22e-42: 163: 14.23
+	Hs
		440366 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		KCNA4_HUMAN (5-231): 5.86e-40: 158: 16.53
+	Hs
		557093 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		KCNA4_HUMAN (5-231): 5.86e-40: 158: 16.53
+	Ce
		234035 SRC2_CAEEL (1-194): 3.61e-19: 91: 17.73		P91563_CAEEL (17-185): 4.35e-41: 151: 28.65
+	Mm
		465776 HCK_MOUSE (2-205): 5.54e-22: 99.5: 18.93		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Hs
		557290 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		BACD2_HUMAN (2-150): 3.1e-37: 143: 25.83
+	Hs
		557514 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		KCND3_HUMAN (1-126): 4.93e-35: 143: 32.31
+	Hs
		987622 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		BACD2_HUMAN (2-150): 3.1e-37: 143: 25.83
+	Mm
		1221234 GRB2_MOUSE (1-60): 2.89e-18: 84.4: 27.87		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Mm
		1296473 ITSN1_MOUSE (6-102): 6.33e-16: 81.6: 22.68		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68