HitPredict

Interactor 1: SOX15 (O60248)
Transcription factor SOX-15 (Protein SOX-12) (Protein SOX-20) (SRY-box transcription factor 15)
Gene: SOX15

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 1281
+	Hs
		881832 SOX10_HUMAN (43-142): 2.82e-37: 137: 51.49		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		818845 SOX9_HUMAN (38-179): 3.1e-36: 135: 40.14		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		727821 SOX5_HUMAN (21-132): 3.84e-35: 133: 41.07		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		818568 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		727938 SOX6_HUMAN (24-222): 2.2e-30: 120: 25.63		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		1332329 SOX17_HUMAN (46-229): 8.91e-31: 118: 36.02		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		1311938 SOX7_HUMAN (9-232): 2.31e-29: 114: 27.89		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Ce
		110065 EGL13_CAEEL (3-146): 1.6e-30: 119: 32.64		ZTF16_CAEEL (895-1271): 2.86e-57: 208: 18.77
+	Hs
		798797 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Dm
		115546 M9PFG6_DROME (30-231): 2.32e-28: 112: 39.11		Q9VF00_DROME (824-1088): 1.87e-41: 166: 20.82
+	Hs
		554520 HM20A_HUMAN (8-209): 3.14e-32: 121: 15.35		GATA1_HUMAN (804-1046): 1.3e-37: 148: 17.55
+	Mm
		620603 SOX4_MOUSE (3-218): 8.11e-32: 122: 35.32		GATA3_MOUSE (870-1017): 2.66e-36: 145: 27.03
+	Hs
		620577 HM20A_HUMAN (8-209): 3.14e-32: 121: 15.35		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		620486 SOX4_HUMAN (3-147): 1.6e-28: 113: 43.45		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		620429 HM20A_HUMAN (8-209): 3.14e-32: 121: 15.35		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		620434 HM20B_HUMAN (6-209): 6.34e-29: 112: 13.40		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Ce
		108367 EGL13_CAEEL (3-146): 1.6e-30: 119: 32.64		ELT6_CAEEL (887-997): 4.1e-23: 104: 32.74
+	Ce
		1095157 EGL13_CAEEL (3-146): 1.6e-30: 119: 32.64		EHN3_CAEEL (1128-1269): 5.94e-24: 104: 21.92