HitPredict

Interactor 1: RL11 (P62913)
Large ribosomal subunit protein uL5 (60S ribosomal protein L11) (CLL-associated antigen KW-12)
Gene: RPL11

Interactor 2: WDR74 (Q6RFH5)
WD repeat-containing protein 74 (NOP seven-associated protein 1)
Gene: WDR74

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 385
+	Hs
		923285 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		FBW1A_HUMAN (24-374): 3.78e-71: 235: 14.44
+	Hs
		923139 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		FBXW7_HUMAN (9-335): 4.45e-68: 229: 14.63
+	Hs
		923246 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		NLE1_HUMAN (169-385): 5.33e-53: 184: 17.49
+	Hs
		792962 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		LIS1_HUMAN (161-382): 1.04e-48: 171: 9.46
+	Hs
		923191 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		KTNB1_HUMAN (196-366): 8.18e-14: 74.9: 18.13