HitPredict

Interactor 1: CCR6 (O54689)
C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (KY411) (CD antigen CD196)
Gene: CCR6

Interactor 2: CCL20 (O89093)
C-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (CC chemokine ST38) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20)
Gene: CCL20

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9862452
Identification Methods	fluorescence technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006935 - chemotaxis GO:0019722 - calcium-mediated signaling GO:0060326 - cell chemotaxis GO:0072678 - T cell migration GO:0072679 - thymocyte migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 367 Mm			1 97
+	Hs
		1009601 ACKR4_HUMAN (2-335): 1.09e-86: 267: 36.72		CCL8_HUMAN (16-97): 1.18e-29: 103: 28.05
+	Hs
		1009610 ACKR4_HUMAN (2-335): 1.09e-86: 267: 36.72		CCL7_HUMAN (16-96): 1.19e-28: 100: 25.93
+	Hs
		1405933 ACKR4_HUMAN (2-335): 1.09e-86: 267: 36.72		CCL13_HUMAN (9-97): 6.16e-28: 99: 23.60
+	Hs
		562855 ACKR4_HUMAN (2-335): 1.09e-86: 267: 36.72		CCL2_HUMAN (16-96): 8.28e-27: 95.9: 23.46
+	Hs
		561026 CXCR5_HUMAN (11-366): 8.2e-82: 255: 32.14		CCL4_HUMAN (3-93): 1.77e-30: 105: 29.67
+	Hs
		907007 CCR6_HUMAN (1-367): 9.17e-83: 258: 74.60		CCL20_HUMAN (3-97): 1.07e-28: 100: 64.21
+	Hs
		190742 ACKR4_HUMAN (2-335): 1.09e-86: 267: 36.72		CCL25_HUMAN (8-95): 3.37e-23: 88.6: 30.44
+	Hs
		518813 CXCR5_HUMAN (11-366): 8.2e-82: 255: 32.14		CCL3_HUMAN (1-94): 1.35e-28: 100: 27.66
+	Hs
		1406889 ACKR4_HUMAN (2-335): 1.09e-86: 267: 36.72		CCL19_HUMAN (17-97): 3.14e-22: 84.3: 28.40
+	Hs
		141767 ACKR4_HUMAN (2-335): 1.09e-86: 267: 36.72		CCL21_HUMAN (24-93): 1.33e-21: 83.9: 33.33
+	Hs
		907075 CCR8_HUMAN (16-356): 1.48e-81: 254: 31.98		CCL18_HUMAN (6-94): 9.59e-27: 95.5: 31.11
+	Hs
		648028 CCR8_HUMAN (16-356): 1.48e-81: 254: 31.98		CCL1_HUMAN (1-90): 4.05e-24: 89.3: 26.67
+	Mm
		533457 CCR3_MOUSE (1-353): 7.81e-78: 245: 33.43		CCL3_MOUSE (1-94): 1.53e-26: 95.1: 25.26
+	Hs
		562875 CXCR5_HUMAN (11-366): 8.2e-82: 255: 32.14		CCL5_HUMAN (14-93): 1.67e-22: 85.1: 27.50
+	Mm
		569686 CCR3_MOUSE (1-353): 7.81e-78: 245: 33.43		CCL4_MOUSE (16-93): 1.56e-26: 95.1: 21.80
+	Hs
		907077 CCR8_HUMAN (16-356): 1.48e-81: 254: 31.98		CCL17_HUMAN (1-91): 1.48e-22: 85.1: 28.57
+	Hs
		191475 CXCR5_HUMAN (11-366): 8.2e-82: 255: 32.14		CCL16_HUMAN (27-89): 5.16e-21: 82: 33.33
+	Hs
		191478 CCR8_HUMAN (16-356): 1.48e-81: 254: 31.98		CCL16_HUMAN (27-89): 5.16e-21: 82: 33.33
+	Hs
		855285 XCR1_HUMAN (9-340): 1.35e-79: 248: 26.51		XCL1_HUMAN (7-96): 1.5e-22: 85.9: 27.96
+	Hs
		191474 CCR1_HUMAN (24-353): 1.38e-77: 244: 33.33		CCL16_HUMAN (27-89): 5.16e-21: 82: 33.33