HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: PLEC (Q9QXS1)
Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6)
Gene: PLEC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30333137
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion GO:0071260 - cellular response to mechanical stimulus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 787 Mm			1 4691
+	Mm
		478561 ITB1_MOUSE (10-786): 0: 731: 43.27		PLEC_MOUSE (1-4691): 0: 1825: 100.00
+	Mm
		549422 ITB2_MOUSE (24-785): 0: 623: 38.45		PLEC_MOUSE (1-4691): 0: 1825: 100.00
+	Hs
		592652 ITB4_HUMAN (5-717): 0: 611: 34.30		PLEC_HUMAN (1-4691): 0: 1780: 93.38
+	Hs
		431675 ITB1_HUMAN (10-786): 0: 725: 43.52		ACTN1_HUMAN (159-906): 2.83e-111: 381: 23.97
+	Gg
		423974 ITB1_CHICK (8-786): 0: 727: 43.75		ACTN1_CHICK (164-906): 7.24e-109: 374: 24.26
+	Mm
		236590 ITB3_MOUSE (1-787): 0: 792: 100.00		SPTB2_MOUSE (1813-3233): 2.97e-13: 79.3: 9.80
+	Hs
		424070 ITB2_HUMAN (26-785): 0: 645: 38.73		SPTB2_HUMAN (1813-3233): 8.63e-13: 77.7: 9.87
+	Hs
		592642 ITB4_HUMAN (5-717): 0: 611: 34.30		DYST_HUMAN (4193-4603): 9.31e-20: 101: 19.22
+	Mm
		549386 ITB2_MOUSE (24-785): 0: 623: 38.45		SPTB2_MOUSE (1813-3233): 2.97e-13: 79.3: 9.80
+	Dm
		262722 TENM_DROME (624-726): 9.89e-16: 84.4: 15.60		ACTN_DROME (183-906): 2.97e-104: 361: 22.96
+	Dm
		55660 TENM_DROME (624-726): 9.89e-16: 84.4: 15.60		A1Z9J1_DROME (514-3085): 2.72e-36: 155: 10.45
+	Dm
		55655 TENM_DROME (624-726): 9.89e-16: 84.4: 15.60		A1Z9J0_DROME (1730-3214): 4.06e-20: 102: 11.08
+	Hs
		1461336 TEN1_HUMAN (362-501): 8.26e-09: 61.6: 9.29		MACF1_HUMAN (4281-4623): 5.43e-18: 95.1: 18.95