HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: SPTB2 (Q62261)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)
Gene: Sptbn1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30333137
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 787 Mm			1 2363
+	Hs
		424070 ITB2_HUMAN (26-785): 0: 645: 38.73		SPTB2_HUMAN (1-2363): 0: 740: 98.05
+	Mm
		549386 ITB2_MOUSE (24-785): 0: 623: 38.45		SPTB2_MOUSE (1-2363): 0: 743: 100.00
+	Mm
		478504 ITB1_MOUSE (10-786): 0: 731: 43.27		ACTN4_MOUSE (53-525): 4.76e-121: 409: 47.58
+	Rn
		92874 ITB1_RAT (10-786): 0: 724: 43.09		D3ZCV0_RAT (53-525): 1.48e-118: 400: 47.58
+	Mm
		86330 ITB3_MOUSE (1-787): 0: 792: 100.00		B9EKJ1_MOUSE (225-2051): 1.98e-81: 302: 23.24
+	Hs
		431675 ITB1_HUMAN (10-786): 0: 725: 43.52		ACTN1_HUMAN (40-775): 1.98e-90: 318: 34.92
+	Mm
		86332 ITB1_MOUSE (10-786): 0: 731: 43.27		B9EKJ1_MOUSE (225-2051): 1.98e-81: 302: 23.24
+	Gg
		423974 ITB1_CHICK (8-786): 0: 727: 43.75		ACTN1_CHICK (40-775): 8.02e-86: 304: 35.05
+	Hs
		424076 ITB2_HUMAN (26-785): 0: 645: 38.73		SPTN1_HUMAN (225-2051): 5.86e-84: 310: 23.51
+	Mm
		236641 ITB3_MOUSE (1-787): 0: 792: 100.00		PLEC_MOUSE (223-1612): 8.49e-39: 162: 9.45
+	Mm
		86334 ITB2_MOUSE (24-785): 0: 623: 38.45		B9EKJ1_MOUSE (225-2051): 1.98e-81: 302: 23.24
+	Mm
		478561 ITB1_MOUSE (10-786): 0: 731: 43.27		PLEC_MOUSE (223-1612): 8.49e-39: 162: 9.45
+	Hs
		592642 ITB4_HUMAN (5-717): 0: 611: 34.30		DYST_HUMAN (267-1813): 8.51e-55: 215: 14.77
+	Mm
		549422 ITB2_MOUSE (24-785): 0: 623: 38.45		PLEC_MOUSE (223-1612): 8.49e-39: 162: 9.45
+	Hs
		592652 ITB4_HUMAN (5-717): 0: 611: 34.30		PLEC_HUMAN (223-1513): 2.82e-38: 161: 9.14
+	Hs
		773802 TENN_HUMAN (581-688): 3.53e-14: 78.9: 22.41		ACTN2_HUMAN (53-525): 7.42e-118: 399: 47.58
+	Dm
		262718 TENM_DROME (624-726): 9.89e-16: 84.4: 15.60		SPTCA_DROME (496-2236): 1.94e-97: 354: 18.79
+	Dm
		262722 TENM_DROME (624-726): 9.89e-16: 84.4: 15.60		ACTN_DROME (48-779): 5.35e-84: 300: 32.52
+	Dm
		55660 TENM_DROME (624-726): 9.89e-16: 84.4: 15.60		A1Z9J1_DROME (249-2074): 3.68e-34: 147: 14.04
+	Dm
		55655 TENM_DROME (624-726): 9.89e-16: 84.4: 15.60		A1Z9J0_DROME (1011-2362): 4.84e-10: 67.9: 10.06