Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: MD2L1 (Q13257)
Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1)
Gene: MAD2L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.767

The method score is based on:

Property Details
Experiments 25852190, 25669885, 25482201, 24151075, 25673878, 26986935, 27939943, 30341343, 11535616, 32152539, 22000412, 21525009, 22100920, 23791783, 25012665, 33961781, 20512932, 23754430, 20212161, 25383541 and 2 others

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Identification Methods affinity chromatography technology, unspecified method, pull down, biochemical, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007094 - mitotic spindle assembly checkpoint signaling
and 3 others

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Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 205
+ Hs
+ Sc
+ Sp
+ At
+ Dm
+ Sc
+ Sp
+ Ce
+ Hs
+ Hs

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Last updated: 15 Jul 2024