Interactor 1: TLR2 (O60603)
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Gene: TLR2

Interactor 2: CXCR4 (P61073)
C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184)
Gene: CXCR4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.55 0.560

The method score is based on:

Property Details
Experiments 18765807, 20802527
Identification Methods fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001666 - response to hypoxia
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0006954 - inflammatory response
and 3 others

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Homologous interactions 0

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Last updated: 15 Jul 2024