HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: H2AV (Q71UI9)
Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2)
Gene: H2AZ2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 128
+	Hs
		243835 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		244634 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48
+	Hs
		244848 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2A1J_HUMAN (5-125): 1.65e-54: 168: 62.30
+	Hs
		244795 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2A1H_HUMAN (5-125): 4.19e-54: 167: 62.30
+	Hs
		243783 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		469949 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		1067021 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00
+	Hs
		631492 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48
+	Hs
		1066979 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2A2C_HUMAN (5-128): 2.15e-54: 168: 62.40
+	Hs
		1067038 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48
+	Hs
		391554 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		555299 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Hs
		1067005 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2A2A_HUMAN (5-125): 7.47e-54: 166: 63.12
+	Hs
		555470 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Hs
		319113 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Sc
		976011 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		H2AZ_YEAST (4-126): 3.22e-39: 129: 66.67
+	Sc
		987582 RSC2_YEAST (87-766): 1.06e-38: 159: 13.49		H2AZ_YEAST (4-126): 3.22e-39: 129: 66.67
+	Hs
		391825 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		555570 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Sc
		728789 BDF1_YEAST (7-303): 2.12e-26: 118: 17.85		H2AZ_YEAST (4-126): 3.22e-39: 129: 66.67