Interactor 1: PEPL (O60437)
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
Gene: PPL

Interactor 2: EVPL (Q92817)
Envoplakin (210 kDa cornified envelope precursor protein) (210 kDa paraneoplastic pemphigus antigen) (p210)
Gene: EVPL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 9412476, 38334954
Identification Methods affinity chromatography technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001533 - cornified envelope
GO:0005198 - structural molecule activity
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0030057 - desmosome
and 5 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1756
Hs

1 2033
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Service provided by Combinatics, Japan

Last updated: 11Aug2025