HitPredict

Interactor 1: PLOD3 (O60568)
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)]
Gene: PLOD3

Interactor 2: CO5A1 (P20908)
Collagen alpha-1(V) chain
Gene: COL5A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen GO:0030199 - collagen fibril organization GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 738 Hs			1 1838
+	Hs
		635450 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO5A1_HUMAN (1-1838): 0: 716: 100.00
+	Hs
		251837 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO4A1_HUMAN (26-547): 3.66e-40: 166: 15.81
+	Hs
		251882 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO7A1_HUMAN (23-434): 7.22e-28: 126: 11.43
+	Hs
		251836 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO1A1_HUMAN (26-483): 9.13e-18: 92.7: 10.52
+	Hs
		251889 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO4A6_HUMAN (1351-1657): 2.36e-16: 88: 32.17
+	Hs
		251884 PLOD3_HUMAN (1-738): 0: 1341: 100.00		COGA1_HUMAN (27-537): 4.19e-15: 83.8: 11.48
+	Hs
		251939 PLOD3_HUMAN (1-738): 0: 1341: 100.00		COMA1_HUMAN (32-388): 4.36e-12: 73.8: 9.26
+	Hs
		251847 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO4A2_HUMAN (25-224): 2.66e-11: 71.5: 10.05
+	Hs
		384312 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO4A1_HUMAN (26-547): 3.66e-40: 166: 15.81
+	Hs
		137019 PLOD2_HUMAN (19-738): 0: 1234: 58.75		CO1A1_HUMAN (26-483): 9.13e-18: 92.7: 10.52
+	Hs
		920922 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO4A4_HUMAN (24-672): 3.02e-22: 107: 13.87
+	Hs
		384249 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO2A1_HUMAN (26-394): 4.44e-19: 96.9: 11.66
+	Hs
		384138 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO1A1_HUMAN (26-483): 9.13e-18: 92.7: 10.52
+	Hs
		1038858 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO4A6_HUMAN (1351-1657): 2.36e-16: 88: 32.17
+	Hs
		1038846 PLOD1_HUMAN (32-738): 0: 1200: 59.38		COGA1_HUMAN (27-537): 4.19e-15: 83.8: 11.48
+	Hs
		471586 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO4A2_HUMAN (25-224): 2.66e-11: 71.5: 10.05
+	Dm
		465904 PLOD_DROME (37-738): 0: 1053: 46.03		CO4A1_DROME (30-220): 3.18e-10: 67.6: 9.05
+	Dm
		1482039 PLOD_DROME (37-738): 0: 1053: 46.03		Q9VMV5_DROME (30-252): 1.64e-09: 65.3: 9.54
+	Hs
		384260 GT252_HUMAN (283-545): 1.07e-95: 311: 27.89		CO2A1_HUMAN (26-394): 4.44e-19: 96.9: 11.66
+	Hs
		384175 GT252_HUMAN (283-545): 1.07e-95: 311: 27.89		CO1A1_HUMAN (26-483): 9.13e-18: 92.7: 10.52