HitPredict

Interactor 1: IMA7 (O60684)
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene: KPNA6

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding GO:0016020 - membrane and 1 others more... GO:0043657 - host cell
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 536 Hs			1 1475
+	Hs
		142505 IMA3_HUMAN (4-536): 4.92e-152: 446: 47.10		NU153_HUMAN (1-1475): 1.51e-176: 569: 100.00
+	Hs
		179034 IMA6_HUMAN (1-536): 2.47e-149: 440: 83.67		NU153_HUMAN (1-1475): 1.51e-176: 569: 100.00
+	Hs
		138653 IMA4_HUMAN (4-536): 2.05e-148: 437: 45.98		NU153_HUMAN (1-1475): 1.51e-176: 569: 100.00
+	Hs
		890283 IMA5_HUMAN (4-536): 9.82e-147: 434: 80.11		NU153_HUMAN (1-1475): 1.51e-176: 569: 100.00
+	Hs
		142506 IMA3_HUMAN (4-536): 4.92e-152: 446: 47.10		RBP2_HUMAN (45-1341): 1.6e-132: 457: 16.25
+	Hs
		138654 IMA4_HUMAN (4-536): 2.05e-148: 437: 45.98		RBP2_HUMAN (45-1341): 1.6e-132: 457: 16.25
+	Hs
		890425 IMA5_HUMAN (4-536): 9.82e-147: 434: 80.11		RBP2_HUMAN (45-1341): 1.6e-132: 457: 16.25
+	Hs
		253676 IMA7_HUMAN (1-536): 4.64e-160: 468: 100.00		P121A_HUMAN (136-1245): 4.05e-34: 145: 9.26
+	Hs
		142603 IMA3_HUMAN (4-536): 4.92e-152: 446: 47.10		P121A_HUMAN (136-1245): 4.05e-34: 145: 9.26
+	Sp
		313992 IMA2_SCHPO (11-536): 2.55e-144: 428: 52.26		NU124_SCHPO (348-1471): 1.19e-39: 163: 10.35
+	Hs
		142575 IMA3_HUMAN (4-536): 4.92e-152: 446: 47.10		RGPD4_HUMAN (827-1399): 7.47e-34: 144: 15.89
+	Hs
		66722 IMA3_HUMAN (4-536): 4.92e-152: 446: 47.10		RGPD3_HUMAN (827-1178): 5.1e-33: 142: 16.85
+	Hs
		138745 IMA4_HUMAN (4-536): 2.05e-148: 437: 45.98		P121A_HUMAN (136-1245): 4.05e-34: 145: 9.26
+	Hs
		911339 IMA5_HUMAN (4-536): 9.82e-147: 434: 80.11		P121A_HUMAN (136-1245): 4.05e-34: 145: 9.26
+	Hs
		253701 IMA7_HUMAN (1-536): 4.64e-160: 468: 100.00		ZRAN1_HUMAN (589-796): 2.08e-21: 103: 16.89
+	Hs
		138638 IMA4_HUMAN (4-536): 2.05e-148: 437: 45.98		NU214_HUMAN (69-1466): 3e-30: 133: 10.99
+	Hs
		911192 IMA5_HUMAN (4-536): 9.82e-147: 434: 80.11		NUP98_HUMAN (907-1474): 7.52e-29: 128: 12.31
+	Hs
		142631 IMA3_HUMAN (4-536): 4.92e-152: 446: 47.10		ZRAN1_HUMAN (589-796): 2.08e-21: 103: 16.89
+	Hs
		138781 IMA4_HUMAN (4-536): 2.05e-148: 437: 45.98		ZRAN1_HUMAN (589-796): 2.08e-21: 103: 16.89
+	Hs
		911421 IMA5_HUMAN (4-536): 9.82e-147: 434: 80.11		ZRAN1_HUMAN (589-796): 2.08e-21: 103: 16.89