HitPredict

Interactor 1: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Interactor 2: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38507240
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 538 Hs			1 1817
+	Hs
		910821 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		NUP98_HUMAN (1-1817): 0: 1468: 100.00
+	At
		1379673 IMPA1_ARATH (4-538): 2.11e-160: 468: 52.78		NUP1_ARATH (1-432): 1.17e-12: 75.6: 15.47
+	Hs
		253601 IMA7_HUMAN (1-538): 1.96e-160: 469: 80.48		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		138638 IMA4_HUMAN (3-538): 5.05e-151: 444: 45.91		NU214_HUMAN (70-677): 6.48e-19: 96.4: 12.06
+	At
		102358 IMPA2_ARATH (4-538): 2.38e-156: 458: 51.30		NUP1_ARATH (1-432): 1.17e-12: 75.6: 15.47
+	Hs
		142505 IMA3_HUMAN (1-538): 2.06e-156: 458: 45.84		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		890283 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		253676 IMA7_HUMAN (1-538): 1.96e-160: 469: 80.48		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63
+	Hs
		911414 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		CHD7_HUMAN (2-355): 6.5e-12: 73.2: 9.09
+	At
		146478 IMPA3_ARATH (4-538): 1.45e-153: 451: 50.47		NUP1_ARATH (1-432): 1.17e-12: 75.6: 15.47
+	Hs
		179034 IMA6_HUMAN (1-538): 3.86e-153: 450: 79.59		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Sp
		313992 IMA2_SCHPO (8-538): 4.8e-144: 427: 49.16		NU124_SCHPO (23-551): 9.9e-19: 95.5: 16.28
+	Hs
		142603 IMA3_HUMAN (1-538): 2.06e-156: 458: 45.84		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63
+	Hs
		911339 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63
+	Hs
		138653 IMA4_HUMAN (3-538): 5.05e-151: 444: 45.91		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		890282 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		911138 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		CHD7_HUMAN (2-355): 6.5e-12: 73.2: 9.09
+	Dm
		1465451 Q9V455_DROME (4-538): 3e-147: 434: 44.49		Q9VGL0_DROME (5-482): 7.78e-14: 79.4: 14.88
+	Hs
		138745 IMA4_HUMAN (3-538): 5.05e-151: 444: 45.91		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63
+	Hs
		911050 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63