HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 758
+	Hs
		530285 H2B1M_HUMAN (1-126): 4.48e-54: 167: 96.03		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		449668 H2B1J_HUMAN (1-126): 6.15e-54: 166: 99.21		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		529892 H2B2E_HUMAN (1-126): 5.57e-54: 166: 98.41		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		1208916 H2B2F_HUMAN (1-126): 2.2e-54: 168: 97.62		PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00
+	Hs
		659962 H2B1O_HUMAN (1-126): 2.89e-54: 167: 97.62		PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00
+	Hs
		1163322 H2B2E_HUMAN (1-126): 5.57e-54: 166: 98.41		PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00
+	Hs
		1372356 H2B1H_HUMAN (1-126): 5.45e-54: 166: 98.41		PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00
+	Hs
		257024 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00
+	Hs
		449810 H2B1J_HUMAN (1-126): 6.15e-54: 166: 99.21		PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00
+	Hs
		943436 H2BFS_HUMAN (1-126): 9.85e-54: 166: 98.41		PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00
+	Hs
		1129608 H2B2E_HUMAN (1-126): 5.57e-54: 166: 98.41		MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48
+	Hs
		1129680 H2B1H_HUMAN (1-126): 5.45e-54: 166: 98.41		MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48
+	Hs
		980769 H2B1C_HUMAN (1-126): 1.08e-53: 166: 99.21		MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48
+	Hs
		1163005 H2B2E_HUMAN (1-126): 5.57e-54: 166: 98.41		SRCAP_HUMAN (168-756): 9.46e-12: 71.2: 11.72
+	Hs
		980867 H2B1C_HUMAN (1-126): 1.08e-53: 166: 99.21		SRCAP_HUMAN (168-756): 9.46e-12: 71.2: 11.72
+	Hs
		256779 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24
+	Hs
		698260 H2B1C_HUMAN (1-126): 1.08e-53: 166: 99.21		MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24
+	Hs
		256961 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46
+	Hs
		980938 H2B1C_HUMAN (1-126): 1.08e-53: 166: 99.21		KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94
+	Hs
		1372265 H2B1H_HUMAN (1-126): 5.45e-54: 166: 98.41		ZN469_HUMAN (2-616): 8.03e-09: 61.6: 9.74