HitPredict

Interactor 1: PHAR2 (O75167)
Phosphatase and actin regulator 2
Gene: PHACTR2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 634 Hs			1 245
+	Hs
		909796 PHAR4_HUMAN (3-634): 2.39e-45: 173: 33.10		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		647096 PHAR4_HUMAN (3-634): 2.39e-45: 173: 33.10		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927287 PHAR4_HUMAN (3-634): 2.39e-45: 173: 33.10		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683531 PHAR4_HUMAN (3-634): 2.39e-45: 173: 33.10		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		910159 MACF1_HUMAN (456-631): 8.87e-32: 134: 17.26		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		257141 PHAR2_HUMAN (1-634): 3.34e-66: 230: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		257135 PHAR2_HUMAN (1-634): 3.34e-66: 230: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		647380 MACF1_HUMAN (456-631): 8.87e-32: 134: 17.26		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927659 MACF1_HUMAN (456-631): 8.87e-32: 134: 17.26		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683813 MACF1_HUMAN (456-631): 8.87e-32: 134: 17.26		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		297821 K0754_HUMAN (106-624): 1.33e-20: 99.2: 11.18		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		297824 K0754_HUMAN (106-624): 1.33e-20: 99.2: 11.18		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		297815 K0754_HUMAN (106-624): 1.33e-20: 99.2: 11.18		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		647025 OTOG_HUMAN (1-521): 2.41e-17: 88.8: 7.68		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927045 MDC1_HUMAN (16-565): 1.39e-17: 89.6: 10.23		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		982258 PHAR4_HUMAN (3-634): 2.39e-45: 173: 33.10		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904838 PHAR4_HUMAN (3-634): 2.39e-45: 173: 33.10		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		684396 MACF1_HUMAN (456-631): 8.87e-32: 134: 17.26		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		982620 MACF1_HUMAN (456-631): 8.87e-32: 134: 17.26		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		905261 MACF1_HUMAN (456-631): 8.87e-32: 134: 17.26		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33