HitPredict

Interactor 1: CATL2 (O60911)
Cathepsin L2 (EC 3.4.22.43) (Cathepsin U) (Cathepsin V)
Gene: CTSV

Interactor 2: CYTM (Q15828)
Cystatin-M (Cystatin-6) (Cystatin-E)
Gene: CST6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.694

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cystatin~Peptidase_C1
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 149
+	Hs
		459297 CATL1_HUMAN (1-334): 1.19e-166: 469: 76.95		CYTM_HUMAN (1-149): 6.3e-53: 166: 100.00
+	Hs
		261579 CATL2_HUMAN (1-334): 6.2e-171: 479: 100.00		CYTN_HUMAN (26-148): 1.05e-44: 145: 29.84
+	Hs
		261578 CATL2_HUMAN (1-334): 6.2e-171: 479: 100.00		CYTC_HUMAN (23-148): 1.45e-43: 142: 33.07
+	Hs
		370138 CATL1_HUMAN (1-334): 1.19e-166: 469: 76.95		CYTN_HUMAN (26-148): 1.05e-44: 145: 29.84
+	Hs
		370028 CATL1_HUMAN (1-334): 1.19e-166: 469: 76.95		CYTC_HUMAN (23-148): 1.45e-43: 142: 33.07
+	Hs
		303702 CATL1_HUMAN (1-334): 1.19e-166: 469: 76.95		CYTF_HUMAN (14-146): 6.51e-38: 128: 29.58
+	Hs
		261581 CATL2_HUMAN (1-334): 6.2e-171: 479: 100.00		KNG1_HUMAN (17-112): 1.11e-12: 66.1: 18.75
+	Hs
		680668 CATS_HUMAN (7-334): 3.46e-140: 401: 49.85		CYTD_HUMAN (7-149): 1.32e-43: 142: 25.52
+	Hs
		370396 CATL1_HUMAN (1-334): 1.19e-166: 469: 76.95		KNG1_HUMAN (17-112): 1.11e-12: 66.1: 18.75
+	Hs
		370142 CATH_HUMAN (28-333): 3.71e-128: 371: 40.13		CYTN_HUMAN (26-148): 1.05e-44: 145: 29.84
+	Hs
		370030 CATH_HUMAN (28-333): 3.71e-128: 371: 40.13		CYTC_HUMAN (23-148): 1.45e-43: 142: 33.07
+	Hs
		485780 CATH_HUMAN (28-333): 3.71e-128: 371: 40.13		CYTD_HUMAN (7-149): 1.32e-43: 142: 25.52
+	Hs
		370398 CATH_HUMAN (28-333): 3.71e-128: 371: 40.13		KNG1_HUMAN (17-112): 1.11e-12: 66.1: 18.75