HitPredict

Interactor 1: CYTC (P01034)
Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin)
Gene: CST3

Interactor 2: CATH (P09668)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H (EC 3.4.22.16); Cathepsin H heavy chain; Cathepsin H light chain]
Gene: CTSH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cystatin~Peptidase_C1
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006955 - immune response
GO:0070062 - extracellular exosome
GO:1904724 - tertiary granule lumen
and 1 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 146
Hs

1 335
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Service provided by Combinatics, Japan

Last updated: 11Aug2025