Interactor 1: MCE1 (O60942)
mRNA-capping enzyme (HCAP1) (HCE) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]
Gene: RNGTT
Interactor 2: MCE1 (O60942)
mRNA-capping enzyme (HCAP1) (HCE) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]
Gene: RNGTT
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27432908 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DSPc~DSPc, DSPc~mRNA_cap_C, mRNA_cap_C~mRNA_cap_C, mRNA_cap_C~mRNA_cap_enzyme, mRNA_cap_enzyme~mRNA_cap_enzyme |
| Common GO terms | GO:0004484 - mRNA guanylyltransferase activity GO:0004651 - polynucleotide 5'-phosphatase activity GO:0004721 - phosphoprotein phosphatase activity GO:0005524 - ATP binding GO:0005525 - GTP binding and 7 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025