HitPredict

Interactor 1: LNX1 (O70263)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: CXAR (P97792)
Coxsackievirus and adenovirus receptor homolog (CAR) (mCAR)
Gene: Cxadr

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	12468544
Identification Methods	two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030165 - PDZ domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Mm			1 365
+	Hs
		1004139 LNX1_HUMAN (1-728): 1.53e-134: 416: 87.57		CXAR_HUMAN (1-365): 1.46e-80: 252: 89.86
+	Mm
		1021888 LNX2_MOUSE (4-728): 1.48e-113: 360: 45.42		CXAR_MOUSE (1-365): 1.88e-82: 257: 100.00
+	Hs
		1004126 LNX2_HUMAN (9-728): 2.7e-114: 362: 45.47		CXAR_HUMAN (1-365): 1.46e-80: 252: 89.86
+	Mm
		266779 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		HECAM_MOUSE (3-337): 1.36e-23: 102: 19.14
+	Hs
		1348399 LNX1_HUMAN (1-728): 1.53e-134: 416: 87.57		NRCAM_HUMAN (2-362): 3.67e-24: 106: 10.69
+	Hs
		1004045 DLG1_HUMAN (359-728): 4.66e-34: 141: 18.64		CXAR_HUMAN (1-365): 1.46e-80: 252: 89.86
+	Hs
		1004055 SCRIB_HUMAN (212-596): 5.03e-32: 136: 20.78		CXAR_HUMAN (1-365): 1.46e-80: 252: 89.86
+	Hs
		1004141 PARD3_HUMAN (233-555): 1.47e-31: 134: 20.50		CXAR_HUMAN (1-365): 1.46e-80: 252: 89.86
+	Hs
		1004044 PTN13_HUMAN (82-515): 4.11e-21: 101: 16.10		CXAR_HUMAN (1-365): 1.46e-80: 252: 89.86
+	Hs
		1353314 PARD3_HUMAN (233-555): 1.47e-31: 134: 20.50		JAM1_HUMAN (1-296): 1.44e-53: 180: 19.54
+	Rn
		1440824 PARD3_RAT (206-555): 2.34e-31: 133: 19.33		JAM1_RAT (3-297): 2.71e-50: 172: 19.87
+	Mm
		313026 MPDZ_MOUSE (264-360): 2.12e-18: 92.5: 29.29		JAM1_MOUSE (3-297): 5.45e-48: 166: 20.52
+	Hs
		944230 PARD3_HUMAN (233-555): 1.47e-31: 134: 20.50		JAM2_HUMAN (26-223): 9.56e-31: 120: 23.22
+	Hs
		1353259 PARD3_HUMAN (233-555): 1.47e-31: 134: 20.50		JAM3_HUMAN (27-264): 1.68e-29: 117: 21.91
+	Mm
		999930 DLG4_MOUSE (454-728): 1.26e-34: 142: 20.07		DCC_MOUSE (2-357): 7.38e-23: 102: 14.10
+	Mm
		1283506 DLG1_MOUSE (351-727): 1.85e-42: 167: 21.68		NRCAM_MOUSE (133-357): 2.87e-13: 73.5: 14.34
+	Mm
		1223607 DLG4_MOUSE (454-728): 1.26e-34: 142: 20.07		NRCAM_MOUSE (133-357): 2.87e-13: 73.5: 14.34
+	Hs
		1122310 SCRIB_HUMAN (212-596): 5.03e-32: 136: 20.78		LRIG1_HUMAN (19-137): 3.36e-10: 63.9: 17.65
+	Hs
		1215975 MAGI3_HUMAN (196-640): 3.08e-18: 92.1: 12.53		NRCAM_HUMAN (2-362): 3.67e-24: 106: 10.69
+	Hs
		1353235 PARD3_HUMAN (233-555): 1.47e-31: 134: 20.50		TITIN_HUMAN (10-144): 2.84e-09: 61.1: 16.30