HitPredict

Interactor 1: TM1L1 (O75674)
TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1)
Gene: TOM1L1

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	15047686, 38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	GAT~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0010008 - endosome membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 476 Hs			1 685
+	Hs
		475949 TM1L2_HUMAN (9-412): 1.02e-118: 359: 32.33		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		241137 TOM1_HUMAN (9-448): 1.15e-118: 358: 31.09		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		276993 STAM2_HUMAN (12-456): 4.7e-90: 285: 17.72		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476541 GGA1_HUMAN (14-437): 9.61e-86: 278: 18.52		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476481 GGA3_HUMAN (14-456): 1.88e-84: 276: 19.34		UBC_HUMAN (1-685): 0: 846: 100.00
+	Bt
		477668 Q58CQ6_BOVIN (14-439): 1.27e-93: 292: 19.07		UBC_BOVIN (1-613): 0: 753: 99.18
+	Sc
		477270 GGA2_YEAST (8-463): 3.74e-83: 269: 18.34		UBI4P_YEAST (381-685): 5e-122: 370: 95.74
+	Mm
		476958 TM1L1_MOUSE (1-476): 2.94e-149: 435: 80.54		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		292209 TOM1_MOUSE (9-458): 2.07e-124: 373: 30.12		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476811 TM1L2_MOUSE (9-412): 1.85e-116: 353: 33.26		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		241134 TOM1_HUMAN (9-448): 1.15e-118: 358: 31.09		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Hs
		277047 STAM2_HUMAN (12-456): 4.7e-90: 285: 17.72		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		292343 STAM2_MOUSE (12-457): 1.15e-95: 300: 18.91		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476884 GGA3_MOUSE (14-449): 1.21e-87: 284: 18.14		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476921 GGA1_MOUSE (14-437): 1.91e-87: 282: 17.90		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		78185 B5DF55_RAT (11-438): 1.29e-84: 272: 16.11		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Mm
		476756 STAM1_MOUSE (11-438): 2.58e-83: 269: 16.56		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		276992 STAM2_HUMAN (12-456): 4.7e-90: 285: 17.72		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		475230 GGA1_HUMAN (14-437): 9.61e-86: 278: 18.52		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		475215 GGA3_HUMAN (14-456): 1.88e-84: 276: 19.34		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70