HitPredict

Interactor 1: PIAS2 (O75928)
E3 SUMO-protein ligase PIAS2 (EC 2.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (E3 SUMO-protein transferase PIAS2) (Msx-interacting zinc finger protein) (Miz1) (PIAS-NY protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)
Gene: PIAS2

Interactor 2: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29180619
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding GO:0016605 - PML body
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 190
+	Hs
		941645 PIAS3_HUMAN (1-621): 0: 666: 55.25		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		278048 PIAS1_HUMAN (1-621): 0: 653: 54.10		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		278131 PIAS1_HUMAN (1-621): 0: 653: 54.10		COP1_HUMAN (125-189): 3.88e-12: 65.8: 32.31
+	Hs
		941155 PIAS4_HUMAN (2-499): 1.7e-172: 502: 43.32		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00