HitPredict

Interactor 1: STX11 (O75558)
Syntaxin-11
Gene: STX11

Interactor 2: STXB2 (Q15833)
Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B)
Gene: STXBP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

Property	Details
Experiments	28514442, 33961781, 19804848, 19884660, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Sec1~Syntaxin
Common GO terms	GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 287 Hs			1 593
+	Mm
		204928 STX1A_MOUSE (1-286): 2.39e-71: 223: 28.67		STXB2_MOUSE (1-593): 0: 706: 94.77
+	Hs
		746199 STX2_HUMAN (1-286): 7.66e-68: 214: 31.82		STXB2_HUMAN (1-593): 0: 709: 100.00
+	Rn
		746113 STX1A_RAT (1-286): 3.03e-71: 223: 28.67		STXB2_RAT (1-593): 0: 689: 93.94
+	Rn
		894401 STX2_RAT (1-278): 5.81e-65: 206: 32.37		STXB2_RAT (1-593): 0: 689: 93.94
+	Bt
		746102 STX1A_BOVIN (1-286): 1.04e-71: 224: 28.67		STXB1_BOVIN (1-591): 0: 632: 63.47
+	Mm
		147920 STX1A_MOUSE (1-286): 2.39e-71: 223: 28.67		STXB1_MOUSE (1-591): 0: 632: 63.47
+	Mm
		147935 STX1B_MOUSE (1-286): 1.33e-71: 223: 32.17		STXB1_MOUSE (1-591): 0: 632: 63.47
+	Rn
		746108 STX1A_RAT (1-286): 3.03e-71: 223: 28.67		STXB1_RAT (1-591): 0: 632: 63.47
+	Rn
		960333 STX1B_RAT (1-286): 1.33e-71: 223: 32.17		STXB1_RAT (1-591): 0: 632: 63.47
+	Hs
		960338 STX1B_HUMAN (1-286): 1.33e-71: 223: 32.17		STXB1_HUMAN (1-591): 0: 632: 63.47
+	Hs
		963424 STX1A_HUMAN (1-286): 2.83e-70: 220: 28.67		STXB1_HUMAN (1-591): 0: 632: 63.47
+	Hs
		746189 STX2_HUMAN (1-286): 7.66e-68: 214: 31.82		STXB1_HUMAN (1-591): 0: 632: 63.47
+	Rn
		894400 STX2_RAT (1-278): 5.81e-65: 206: 32.37		STXB1_RAT (1-591): 0: 632: 63.47
+	Hs
		286641 STX11_HUMAN (1-287): 1.26e-63: 203: 100.00		STXB1_HUMAN (1-591): 0: 632: 63.47
+	Hs
		963409 STX4_HUMAN (1-286): 1.55e-58: 190: 27.53		STXB1_HUMAN (1-591): 0: 632: 63.47
+	Dm
		1059140 STX1A_DROME (10-286): 7.21e-68: 214: 26.72		ROP_DROME (4-587): 0: 600: 54.33
+	Ce
		194913 STX1A_CAEEL (2-286): 5.02e-66: 209: 28.42		UNC18_CAEEL (4-588): 0: 588: 52.78
+	Hs
		125717 STX2_HUMAN (1-286): 7.66e-68: 214: 31.82		STXB3_HUMAN (1-592): 0: 577: 46.14
+	Hs
		125737 STX4_HUMAN (1-286): 1.55e-58: 190: 27.53		STXB3_HUMAN (1-592): 0: 577: 46.14
+	Dm
		1172792 STX1A_DROME (10-286): 7.21e-68: 214: 26.72		SLY1_DROME (20-588): 1.3e-136: 413: 17.14