Interactor 1: DNM3B (O88509)
DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB)
Gene: Dnmt3b

Interactor 2: DNM3L (Q9CWR8)
DNA (cytosine-5)-methyltransferase 3-like
Gene: Dnmt3l

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.852

The method score is based on:

Property Details
Experiments 16543361, 17687327, 24074865
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, molecular sieving
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ADD_DNMT3~ADD_DNMT3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000792 - heterochromatin
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 859
Mm

1 421
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024