Interactor 1: SOCS2 (O88582)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2)
Gene: SOCS2

Interactor 2: SOCS3 (O88583)
Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3)
Gene: SOCS3

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16956890
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~SOCS_box
Common GO terms GO:0005942 - phosphatidylinositol 3-kinase complex
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT
GO:0016567 - protein ubiquitination
GO:0032355 - response to estradiol
GO:0035556 - intracellular signal transduction
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 198
Rn

1 225
+ Hs
+ Rn
+ Mm
+ Mm
+ Rn
+ Hs
+ Rn
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm

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Last updated: 15 Jul 2024