HitPredict

Interactor 1: TRIO (O75962)
Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein)
Gene: TRIO

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras, Ras~RhoGEF, Ras~SOS1_NGEF_PH
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3097 Hs			1 196
+	Hs
		299534 TRIO_HUMAN (41-3097): 0: 2373: 100.00		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		299530 TRIO_HUMAN (41-3097): 0: 2373: 100.00		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		299535 TRIO_HUMAN (41-3097): 0: 2373: 100.00		RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53
+	Hs
		299529 TRIO_HUMAN (41-3097): 0: 2373: 100.00		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49
+	Hs
		238812 KALRN_HUMAN (53-3092): 0: 1937: 59.58		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		988495 ARHGP_HUMAN (1241-1632): 3.35e-119: 393: 34.00		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		962227 ARHGP_HUMAN (1241-1632): 3.35e-119: 393: 34.00		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		955340 ARHGP_HUMAN (1241-1632): 3.35e-119: 393: 34.00		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49
+	Hs
		319060 K0754_HUMAN (142-1887): 9.58e-103: 373: 11.01		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		319057 K0754_HUMAN (142-1887): 9.58e-103: 373: 11.01		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		319059 K0754_HUMAN (142-1887): 9.58e-103: 373: 11.01		RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00
+	Hs
		319049 K0754_HUMAN (142-1887): 9.58e-103: 373: 11.01		RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57
+	Hs
		319064 K0754_HUMAN (142-1887): 9.58e-103: 373: 11.01		RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53
+	Hs
		319046 K0754_HUMAN (142-1887): 9.58e-103: 373: 11.01		RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16
+	Hs
		319056 K0754_HUMAN (142-1887): 9.58e-103: 373: 11.01		RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54
+	Ce
		1041914 Q7KPP4_CAEEL (789-2378): 6.19e-96: 348: 13.34		RAC1_CAEEL (1-196): 3.83e-80: 238: 53.57
+	Hs
		126409 K0754_HUMAN (142-1887): 9.58e-103: 373: 11.01		RHOD_HUMAN (7-182): 3.38e-66: 203: 53.98
+	Ce
		110134 Q7KPP4_CAEEL (789-2378): 6.19e-96: 348: 13.34		G5EBV3_CAEEL (2-196): 7.16e-76: 227: 48.72
+	Hs
		533816 MCF2_HUMAN (130-839): 2.01e-84: 301: 15.94		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		533815 MCF2_HUMAN (130-839): 2.01e-84: 301: 15.94		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49