HitPredict

Interactor 1: RNF8 (O76064)
E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8)
Gene: RNF8

Interactor 2: S10A7 (P31151)
Protein S100-A7 (Psoriasin) (S100 calcium-binding protein A7)
Gene: S100A7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35831895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 485 Hs			1 101
+	Hs
		302574 RNF8_HUMAN (1-485): 2.14e-179: 513: 100.00		HORN_HUMAN (2-101): 2.06e-30: 114: 18.45
+	Hs
		302547 RNF8_HUMAN (1-485): 2.14e-179: 513: 100.00		FILA2_HUMAN (4-101): 5.98e-26: 101: 23.76
+	Hs
		302321 RNF8_HUMAN (1-485): 2.14e-179: 513: 100.00		S10A9_HUMAN (4-101): 1.24e-27: 98.8: 23.53
+	Hs
		302316 RNF8_HUMAN (1-485): 2.14e-179: 513: 100.00		S10A8_HUMAN (2-94): 1.46e-22: 85.3: 22.92
+	Hs
		302372 RNF8_HUMAN (1-485): 2.14e-179: 513: 100.00		FILA_HUMAN (4-101): 3.63e-19: 82.7: 21.78
+	Hs
		623418 RO52_HUMAN (390-483): 4.33e-26: 112: 31.58		HORN_HUMAN (2-101): 2.06e-30: 114: 18.45
+	Hs
		623132 RO52_HUMAN (390-483): 4.33e-26: 112: 31.58		S10A7_HUMAN (1-101): 1.23e-30: 106: 100.00
+	Hs
		623137 RO52_HUMAN (390-483): 4.33e-26: 112: 31.58		S10AB_HUMAN (2-95): 5.92e-31: 106: 32.99
+	Hs
		1295714 TRIM6_HUMAN (389-468): 9.95e-23: 102: 24.14		HORN_HUMAN (2-101): 2.06e-30: 114: 18.45
+	Hs
		623373 RO52_HUMAN (390-483): 4.33e-26: 112: 31.58		FILA2_HUMAN (4-101): 5.98e-26: 101: 23.76
+	Hs
		445186 LONF2_HUMAN (185-483): 2.89e-30: 126: 15.20		S10A6_HUMAN (2-92): 1.32e-22: 85.3: 23.40
+	Hs
		682586 UHRF1_HUMAN (206-472): 2.64e-24: 108: 14.57		S100P_HUMAN (4-93): 1.44e-29: 103: 26.88
+	Hs
		444897 RO52_HUMAN (390-483): 4.33e-26: 112: 31.58		S10A9_HUMAN (4-101): 1.24e-27: 98.8: 23.53
+	Hs
		706258 TRI11_HUMAN (392-472): 1.19e-23: 105: 26.19		S10A2_HUMAN (1-92): 7.08e-28: 98.8: 22.11
+	Hs
		424134 RO52_HUMAN (390-483): 4.33e-26: 112: 31.58		S10A8_HUMAN (2-94): 1.46e-22: 85.3: 22.92
+	Hs
		623094 RO52_HUMAN (390-483): 4.33e-26: 112: 31.58		FILA_HUMAN (4-101): 3.63e-19: 82.7: 21.78
+	Hs
		445236 TRI11_HUMAN (392-472): 1.19e-23: 105: 26.19		S10A6_HUMAN (2-92): 1.32e-22: 85.3: 23.40
+	Hs
		623552 RO52_HUMAN (390-483): 4.33e-26: 112: 31.58		S10AE_HUMAN (4-84): 2.12e-18: 74.9: 21.69
+	Hs
		424228 COP1_HUMAN (379-472): 3.42e-11: 67.8: 24.47		S10A8_HUMAN (2-94): 1.46e-22: 85.3: 22.92