HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: WDR43 (Q15061)
WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog)
Gene: WDR43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	37689310, 23891004
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 677
+	Hs
		302772 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		LIS1_HUMAN (119-440): 1.36e-45: 169: 15.15
+	Hs
		302801 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		WDR5_HUMAN (264-418): 1.21e-18: 89.5: 8.33
+	Hs
		1380064 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		FBXW7_HUMAN (5-295): 3.52e-60: 216: 16.08
+	Dm
		1463899 WDS_DROME (137-339): 6.23e-48: 166: 20.69		WDS_DROME (5-197): 2.46e-39: 150: 19.00
+	Hs
		1334151 POC1B_HUMAN (92-339): 5.35e-60: 201: 20.97		POC1A_HUMAN (5-153): 3.57e-26: 113: 14.77
+	Hs
		921980 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		COPA_HUMAN (126-302): 9.97e-31: 131: 14.53
+	Hs
		261440 TBL1R_HUMAN (3-283): 2.29e-63: 211: 25.52		TBL1X_HUMAN (259-408): 3.15e-10: 65.2: 9.15
+	Hs
		1410246 TBL1R_HUMAN (3-283): 2.29e-63: 211: 25.52		TBL1Y_HUMAN (259-408): 6.69e-10: 64.1: 7.88
+	Hs
		984306 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		NLE1_HUMAN (199-622): 8.78e-27: 116: 8.35
+	Hs
		965141 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		WDR5_HUMAN (264-418): 1.21e-18: 89.5: 8.33
+	Hs
		1180240 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		SMU1_HUMAN (117-336): 3e-15: 81.1: 18.62
+	Hs
		845264 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		LIS1_HUMAN (119-440): 1.36e-45: 169: 15.15
+	Sc
		793908 TAF5_YEAST (124-339): 2.23e-35: 138: 19.48		TAF5_YEAST (78-354): 1.69e-21: 101: 18.07
+	Hs
		964894 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		TBL3_HUMAN (55-421): 6.07e-35: 143: 12.73
+	Hs
		921858 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		COPA_HUMAN (126-302): 9.97e-31: 131: 14.53
+	Hs
		1450936 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		NLE1_HUMAN (199-622): 8.78e-27: 116: 8.35
+	Hs
		965071 WDR5B_HUMAN (2-132): 1.34e-25: 106: 22.06		WDR5_HUMAN (264-418): 1.21e-18: 89.5: 8.33
+	Hs
		938199 SEC13_HUMAN (28-281): 8.1e-19: 87.4: 29.64		WDR5_HUMAN (264-418): 1.21e-18: 89.5: 8.33
+	Hs
		965276 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		WDR5_HUMAN (264-418): 1.21e-18: 89.5: 8.33
+	Hs
		964797 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		WDR5_HUMAN (264-418): 1.21e-18: 89.5: 8.33