HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: HELLS (Q9NRZ9)
Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)
Gene: HELLS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40, SNF2-rel_dom~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 838
+	Hs
		1380192 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		HELLS_HUMAN (1-838): 0: 771: 100.00
+	Hs
		1132879 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		CHD4_HUMAN (51-828): 0: 631: 25.27
+	Hs
		1350646 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		CHD6_HUMAN (7-836): 0: 628: 26.09
+	Hs
		984089 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		CHD3_HUMAN (50-828): 0: 653: 24.79
+	Hs
		160120 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		CHD1_HUMAN (47-835): 0: 614: 26.26
+	Hs
		703359 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		SMCA1_HUMAN (104-833): 0: 613: 31.43
+	Dm
		674032 EBI_DROME (8-181): 1.64e-46: 169: 27.32		BRM_DROME (29-809): 0: 615: 28.23
+	Hs
		903450 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		SMCA4_HUMAN (8-838): 0: 590: 22.96
+	Hs
		1088581 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		CHD3_HUMAN (50-828): 0: 653: 24.79
+	Hs
		1088500 SNR40_HUMAN (234-339): 2.01e-15: 78.2: 19.81		CHD3_HUMAN (50-828): 0: 653: 24.79
+	Sc
		744288 TAF5_YEAST (124-339): 2.23e-35: 138: 19.48		CHD1_YEAST (44-831): 0: 591: 28.91
+	Hs
		965260 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		CHD8_HUMAN (2-836): 0: 638: 26.59
+	Hs
		964955 WDR5_HUMAN (225-339): 5.15e-18: 85.1: 15.65		CHD4_HUMAN (51-828): 0: 631: 25.27
+	Hs
		1410248 TBL1Y_HUMAN (58-218): 5.76e-14: 74.3: 28.24		CHD8_HUMAN (2-836): 0: 638: 26.59
+	Hs
		160123 SNR40_HUMAN (234-339): 2.01e-15: 78.2: 19.81		CHD1_HUMAN (47-835): 0: 614: 26.26
+	Hs
		703360 SNR40_HUMAN (234-339): 2.01e-15: 78.2: 19.81		SMCA1_HUMAN (104-833): 0: 613: 31.43
+	Hs
		903453 SNR40_HUMAN (234-339): 2.01e-15: 78.2: 19.81		SMCA4_HUMAN (8-838): 0: 590: 22.96
+	Hs
		302881 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		CHD1L_HUMAN (218-755): 1.81e-105: 347: 40.30
+	Hs
		1387556 SNR40_HUMAN (234-339): 2.01e-15: 78.2: 19.81		SMRCD_HUMAN (206-744): 1.54e-92: 315: 37.59
+	Sc
		734416 TAF5_YEAST (124-339): 2.23e-35: 138: 19.48		BTAF1_YEAST (211-826): 4.4e-70: 254: 30.83