HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: CALR (P27797)
Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60)
Gene: CALR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	20562859, 19154346
Identification Methods	anti tag coimmunoprecipitation, surface plasmon resonance, nuclear magnetic resonance, x-ray crystallography
Interaction Type	association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005790 - smooth endoplasmic reticulum GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 417
+	Hs
		653539 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		CALR_HUMAN (18-417): 0: 519: 100.00
+	Mm
		536160 GBRAP_MOUSE (1-117): 8.06e-57: 173: 100.00		CALR_MOUSE (1-417): 0: 518: 94.25
+	Rn
		576258 GBRAP_RAT (1-117): 8.06e-57: 173: 100.00		CALR_RAT (1-417): 0: 517: 93.53
+	Hs
		653723 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		CALR_HUMAN (18-417): 0: 519: 100.00
+	Zm
		21700 B6SUL0_MAIZE (3-117): 3.52e-63: 189: 60.00		A0A1D6HWM2_MAIZE (20-417): 1.29e-144: 419: 50.87
+	Hs
		654219 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		CALX_HUMAN (20-416): 1.51e-145: 428: 34.39
+	Hs
		654757 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		CALX_HUMAN (20-416): 1.51e-145: 428: 34.39