HitPredict

Interactor 1: LIN7C (O88952)
Protein lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Interactor 2: PALS1 (Q9JLB2)
Protein PALS1 (MAGUK p55 subfamily member 5) (Protein associated with Lin-7 1)
Gene: PALS1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16186258
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	L27~L27, Guanylate_kin~PDZ, PDZ~PDZ, PDZ~SH3_2
Common GO terms	GO:0002011 - morphogenesis of an epithelial sheet GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 197 Mm			1 675
+	Hs
		1325321 LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00		PALS1_HUMAN (1-675): 0: 565: 96.74
+	Hs
		1325312 LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69		PALS1_HUMAN (1-675): 0: 565: 96.74
+	Hs
		1450016 LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00		PALS2_HUMAN (124-674): 5.11e-145: 434: 34.05
+	Hs
		168758 LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00		CSKP_HUMAN (9-674): 4.04e-140: 434: 26.46
+	Mm
		267260 LIN7C_MOUSE (1-197): 1.56e-57: 181: 100.00		CSKP_MOUSE (9-674): 5.92e-140: 434: 26.46
+	Hs
		1437597 LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69		PALS2_HUMAN (124-674): 5.11e-145: 434: 34.05
+	Hs
		168750 LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69		CSKP_HUMAN (9-674): 4.04e-140: 434: 26.46
+	Mm
		267259 LIN7B_MOUSE (1-196): 1e-54: 174: 85.71		CSKP_MOUSE (9-674): 5.92e-140: 434: 26.46
+	Hs
		1122734 LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00		MPP2_HUMAN (140-674): 1.8e-140: 424: 33.22
+	Hs
		1122731 LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69		MPP2_HUMAN (140-674): 1.8e-140: 424: 33.22
+	Hs
		1212215 LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00		MPP7_HUMAN (117-674): 1.3e-129: 396: 35.75
+	Hs
		1212210 LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69		MPP7_HUMAN (117-674): 1.3e-129: 396: 35.75
+	Hs
		1103525 LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00		MPP3_HUMAN (118-675): 1.21e-121: 376: 32.72
+	Hs
		1103523 LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69		MPP3_HUMAN (118-675): 1.21e-121: 376: 32.72
+	Hs
		1006110 LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00		DLG4_HUMAN (214-344): 1.64e-18: 92: 14.39
+	Hs
		1091580 LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00		DLG1_HUMAN (53-336): 1.68e-18: 92: 14.10
+	Mm
		313202 LIN7C_MOUSE (1-197): 1.56e-57: 181: 100.00		DLG1_MOUSE (53-336): 6.47e-18: 90.5: 12.05
+	Hs
		1006105 LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69		DLG4_HUMAN (214-344): 1.64e-18: 92: 14.39
+	Hs
		1091570 LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69		DLG1_HUMAN (53-336): 1.68e-18: 92: 14.10
+	Rn
		723908 LIN7B_RAT (1-196): 1.78e-54: 174: 85.71		DLG4_RAT (214-344): 1.41e-18: 92: 14.39