HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: SNAB (Q9H115)
Beta-soluble NSF attachment protein (SNAP-beta) (N-ethylmaleimide-sensitive factor attachment protein beta)
Gene: NAPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNAP~Synaptobrevin
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 298
+	Hs
		328650 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Hs
		278559 VAMP4_HUMAN (3-73): 1.95e-25: 94.6: 29.58		SNAB_HUMAN (1-298): 3.44e-116: 338: 100.00
+	Mm
		704313 VAMP2_MOUSE (2-75): 3.53e-25: 93: 39.19		SNAB_MOUSE (1-298): 3.44e-116: 338: 100.00
+	Dm
		1171606 Q7JYX5_DROME (4-96): 8e-33: 115: 31.18		SNAP_DROME (5-292): 1.03e-103: 306: 62.15
+	Hs
		907987 VAMP7_HUMAN (4-96): 3.28e-25: 96.1: 31.18		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Hs
		278485 VAMP4_HUMAN (3-73): 1.95e-25: 94.6: 29.58		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Hs
		932991 VAMP2_HUMAN (2-75): 3.53e-25: 93: 39.19		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Hs
		933050 VAMP8_HUMAN (2-73): 2.39e-25: 93: 26.39		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Dm
		614895 SYB_DROME (2-88): 1.37e-29: 105: 39.08		SNAP_DROME (5-292): 1.03e-103: 306: 62.15
+	Hs
		933010 VAMP3_HUMAN (2-72): 1.48e-24: 91.1: 38.03		SNAA_HUMAN (1-293): 7.27e-109: 319: 83.96
+	Zm
		31396 A0A1D6KH00_MAIZE (5-91): 6.21e-33: 122: 28.74		A0A1D6PZ82_MAIZE (5-272): 1.44e-88: 269: 37.55
+	Hs
		328727 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30
+	Hs
		908047 VAMP7_HUMAN (4-96): 3.28e-25: 96.1: 31.18		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30
+	Hs
		278549 VAMP4_HUMAN (3-73): 1.95e-25: 94.6: 29.58		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30
+	Hs
		1407039 VAMP8_HUMAN (2-73): 2.39e-25: 93: 26.39		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30
+	Hs
		989376 VAMP2_HUMAN (2-75): 3.53e-25: 93: 39.19		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30
+	Hs
		1154723 VAMP3_HUMAN (2-72): 1.48e-24: 91.1: 38.03		SNAG_HUMAN (4-251): 6.32e-69: 218: 24.30
+	Dm
		1263454 Q7JYX5_DROME (4-96): 8e-33: 115: 31.18		Q9U6R9_DROME (4-265): 3.28e-59: 193: 19.70
+	Dm
		614932 SYB_DROME (2-88): 1.37e-29: 105: 39.08		Q9U6R9_DROME (4-265): 3.28e-59: 193: 19.70
+	Dm
		1263460 Q7JYX5_DROME (4-96): 8e-33: 115: 31.18		Q9VH25_DROME (42-265): 8.65e-52: 173: 19.03