HitPredict

Interactor 1: TBC12 (O96904)
Drainin (TBC1 domain family member 12 homolog)
Gene: phgA

Interactor 2: RAB14 (P36410)
Ras-related protein Rab-14 (EC 3.6.5.2) (Rab4-like GTPase)
Gene: RAB14

Species: Dictyostelium discoideum

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	18636095
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0006971 - hypotonic response GO:0031164 - contractile vacuolar membrane GO:0033298 - contractile vacuole organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 438 Dd			1 206
+	Hs
		895106 TB10B_HUMAN (32-434): 6.01e-87: 283: 17.56		RAB2A_HUMAN (5-192): 9.08e-98: 284: 65.43
+	Hs
		233033 TBC12_HUMAN (8-433): 1.31e-93: 300: 35.27		RAB4A_HUMAN (1-179): 1.4e-83: 248: 64.80
+	Hs
		1079972 TBC14_HUMAN (9-433): 2.97e-90: 289: 34.42		RB11B_HUMAN (4-205): 9.79e-86: 253: 45.93
+	Hs
		233036 TBC12_HUMAN (8-433): 1.31e-93: 300: 35.27		RB11A_HUMAN (4-204): 4.01e-80: 239: 46.86
+	Dm
		1197047 EVI5_DROME (214-435): 5.26e-76: 254: 24.89		Q86BK8_DROME (3-206): 1.94e-96: 281: 68.57
+	Hs
		232698 TBCD4_HUMAN (17-431): 1.13e-70: 244: 18.71		RAB2B_HUMAN (4-196): 6.71e-98: 284: 63.21
+	Hs
		914423 TBC14_HUMAN (9-433): 2.97e-90: 289: 34.42		RB11A_HUMAN (4-204): 4.01e-80: 239: 46.86
+	Os
		1130873 Q5SMT0_ORYSJ (7-428): 1.8e-81: 266: 18.35		Q6YY17_ORYSJ (5-180): 4.3e-83: 247: 64.77
+	Os
		1130874 Q5SMT0_ORYSJ (7-428): 1.8e-81: 266: 18.35		Q7XHP7_ORYSJ (4-205): 2.85e-81: 242: 39.41
+	Hs
		234378 EVI5_HUMAN (158-438): 1.21e-75: 253: 19.72		RB11B_HUMAN (4-205): 9.79e-86: 253: 45.93
+	Hs
		894747 TBC9B_HUMAN (62-426): 5.52e-73: 250: 13.93		RAB8A_HUMAN (1-204): 6.56e-82: 244: 38.24
+	Hs
		234370 EVI5_HUMAN (158-438): 1.21e-75: 253: 19.72		RB11A_HUMAN (4-204): 4.01e-80: 239: 46.86
+	Hs
		592076 RBGP1_HUMAN (145-429): 8e-71: 243: 24.48		RAB4A_HUMAN (1-179): 1.4e-83: 248: 64.80
+	Hs
		894778 TBC15_HUMAN (46-432): 8.82e-74: 246: 14.94		RAB8A_HUMAN (1-204): 6.56e-82: 244: 38.24
+	Hs
		914176 TBCD1_HUMAN (18-431): 2.74e-71: 245: 18.87		RB11A_HUMAN (4-204): 4.01e-80: 239: 46.86
+	Hs
		914482 RBGP1_HUMAN (145-429): 8e-71: 243: 24.48		RB11A_HUMAN (4-204): 4.01e-80: 239: 46.86
+	Ce
		107453 Q23419_CAEEL (18-422): 9.94e-70: 239: 16.18		G5EFC1_CAEEL (1-206): 4.13e-81: 242: 37.50
+	Hs
		914275 EVI5L_HUMAN (155-438): 4.43e-69: 235: 19.16		RB11A_HUMAN (4-204): 4.01e-80: 239: 46.86
+	Os
		772871 Q5SMT0_ORYSJ (7-428): 1.8e-81: 266: 18.35		RIC2_ORYSJ (5-185): 1.63e-59: 187: 50.83
+	Dm
		185716 EVI5_DROME (214-435): 5.26e-76: 254: 24.89		O18335_DROME (5-188): 3.31e-61: 191: 51.09