Interactor 1: SIX3 (O95343)
Homeobox protein SIX3 (Sine oculis homeobox homolog 3)
Gene: SIX3
Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 0.60 | 0.527 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12441302 |
| Identification Methods | two hybrid, pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
