HitPredict

Interactor 1: TBCD8 (O95759)
TBC1 domain family member 8 (AD 3) (Vascular Rab-GAP/TBC-containing protein)
Gene: TBC1D8

Interactor 2: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	34079125, 37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 218
+	Hs
		344402 TBCD8_HUMAN (1-1140): 0: 1098: 100.00		RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33
+	Hs
		956351 TBCD9_HUMAN (1-1101): 0: 1007: 47.73		RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92
+	Dm
		1285645 EVI5_DROME (400-1139): 2.39e-119: 389: 15.83		Q86BK8_DROME (3-218): 3.4e-94: 276: 56.94
+	Hs
		1155376 EVI5L_HUMAN (398-1080): 1.07e-117: 385: 16.16		RB11B_HUMAN (3-217): 4.38e-83: 247: 43.26
+	Hs
		976478 EVI5L_HUMAN (398-1080): 1.07e-117: 385: 16.16		RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33
+	Dm
		197387 EVI5_DROME (400-1139): 2.39e-119: 389: 15.83		O18335_DROME (3-216): 4.03e-81: 242: 44.39
+	Hs
		631036 RBGP1_HUMAN (323-981): 1.21e-94: 328: 17.18		RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00
+	Hs
		976687 RBGP1_HUMAN (323-981): 1.21e-94: 328: 17.18		RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33
+	Hs
		956320 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92
+	Os
		1209946 Q5SMT0_ORYSJ (266-743): 2.56e-81: 282: 15.91		Q6YY17_ORYSJ (9-197): 2.48e-93: 273: 55.03
+	Hs
		247144 TBCD4_HUMAN (367-884): 3.59e-82: 295: 18.10		RAB2B_HUMAN (10-218): 1.43e-81: 244: 51.87
+	Hs
		976376 TBCD1_HUMAN (367-843): 2.5e-80: 288: 17.04		RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33
+	Hs
		1155398 TBC14_HUMAN (366-772): 1.47e-79: 277: 17.74		RB11B_HUMAN (3-217): 4.38e-83: 247: 43.26
+	Hs
		976628 TBC14_HUMAN (366-772): 1.47e-79: 277: 17.74		RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33
+	Hs
		631025 TBD2B_HUMAN (479-727): 3.25e-30: 131: 33.20		RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00
+	Hs
		976670 TBD2B_HUMAN (479-727): 3.25e-30: 131: 33.20		RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33
+	Hs
		248977 EVI5_HUMAN (822-1139): 3.59e-20: 98.8: 11.11		RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33
+	Hs
		248986 EVI5_HUMAN (822-1139): 3.59e-20: 98.8: 11.11		RB11B_HUMAN (3-217): 4.38e-83: 247: 43.26
+	Sc
		800381 GYP3_YEAST (494-721): 1.38e-29: 127: 31.39		YPT31_YEAST (1-184): 1.21e-54: 175: 47.28