HitPredict

Interactor 1: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Interactor 2: RN125 (Q96EQ8)
E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)
Gene: RNF125

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.704

The method score is based on:

Property Details
Experiments 31827077, 17460044, 37230297, 37541247
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0008270 - zinc ion binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 925
Hs

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Last updated: 11Aug2025