HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: UBP10 (P53874)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: UBP10

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26149687, 30681413, 29288197, 37968396
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 792
+	Sc
		355960 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		UBP10_YEAST (1-770): 5.85e-168: 506: 100.00
+	Hs
		777048 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP8_HUMAN (9-736): 4.31e-125: 403: 16.25
+	Hs
		1087489 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP22_HUMAN (280-738): 2.61e-104: 332: 19.34
+	Hs
		707794 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP22_HUMAN (280-738): 2.61e-104: 332: 19.34
+	Hs
		271037 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP2_HUMAN (167-737): 1.17e-99: 322: 15.68
+	Hs
		707665 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP51_HUMAN (300-736): 1.36e-94: 312: 20.26
+	Hs
		1087318 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP7_HUMAN (162-786): 4e-90: 308: 13.21
+	Hs
		707705 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP7_HUMAN (162-786): 4e-90: 308: 13.21
+	Hs
		259286 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP12_HUMAN (344-734): 2.97e-91: 292: 22.36
+	Hs
		707807 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP3_HUMAN (255-739): 1.58e-88: 290: 18.47
+	Hs
		707785 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP21_HUMAN (363-736): 1.15e-87: 289: 20.16
+	Hs
		905383 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP46_HUMAN (340-733): 1.57e-86: 280: 20.98
+	Hs
		905394 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		UBP46_HUMAN (340-733): 1.57e-86: 280: 20.98
+	Sc
		355977 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		UBP3_YEAST (16-734): 4.12e-79: 275: 15.39
+	Hs
		707772 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85
+	Hs
		1087411 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP42_HUMAN (261-776): 8.85e-76: 270: 17.66
+	Hs
		1121182 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		UBP39_HUMAN (135-737): 8.42e-77: 260: 13.66
+	Sc
		355943 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		UBP8_YEAST (330-731): 1.97e-74: 251: 19.72
+	Hs
		1087499 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP20_HUMAN (462-738): 2.62e-24: 111: 30.51
+	Hs
		707745 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP44_HUMAN (454-732): 3.22e-15: 81.6: 24.68