HitPredict

Interactor 1: O97102 (O97102)
Small ubiquitin-related modifier (SUMO)
Gene: Sumo

Interactor 2: Q9XYM5 (Q9XYM5)
LD27861p (Suppressor of variegation 2-10, isoform E) (Zimp-B)
Gene: Su(var)2-10

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	31901446
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Rad60-SLD~zf-MIZ
Common GO terms	GO:0005634 - nucleus GO:0016925 - protein sumoylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 90 Dm			1 522
+	Hs
		939243 SUMO3_HUMAN (1-90): 5.79e-37: 121: 69.15		PIAS3_HUMAN (1-509): 0: 556: 41.55
+	Hs
		964529 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		PIAS3_HUMAN (1-509): 0: 556: 41.55
+	Mm
		236336 SUMO1_MOUSE (7-88): 2.33e-32: 109: 53.66		PIAS3_MOUSE (1-509): 0: 555: 41.63
+	Hs
		297530 SUMO3_HUMAN (1-90): 5.79e-37: 121: 69.15		PIAS1_HUMAN (1-510): 0: 531: 41.52
+	Hs
		297541 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		PIAS1_HUMAN (1-510): 0: 531: 41.52
+	Hs
		297778 SUMO3_HUMAN (1-90): 5.79e-37: 121: 69.15		PIAS2_HUMAN (1-519): 2.39e-180: 522: 39.93
+	Hs
		107789 SUMO5_HUMAN (1-88): 3.7e-33: 111: 47.42		PIAS1_HUMAN (1-510): 0: 531: 41.52
+	Rn
		1220400 SUMO3_RAT (1-88): 3.42e-37: 122: 69.57		PIAS2_RAT (1-519): 8.84e-180: 519: 39.74
+	Hs
		297561 SUMO1_HUMAN (7-88): 2.33e-32: 109: 53.66		PIAS1_HUMAN (1-510): 0: 531: 41.52
+	Hs
		297781 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		PIAS2_HUMAN (1-519): 2.39e-180: 522: 39.93
+	Hs
		107790 SUMO5_HUMAN (1-88): 3.7e-33: 111: 47.42		PIAS2_HUMAN (1-519): 2.39e-180: 522: 39.93
+	Hs
		939211 SUMO3_HUMAN (1-90): 5.79e-37: 121: 69.15		PIAS4_HUMAN (1-423): 7.05e-174: 501: 43.06
+	Hs
		964366 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		PIAS4_HUMAN (1-423): 7.05e-174: 501: 43.06
+	Rn
		81598 SUMO3_RAT (1-88): 3.42e-37: 122: 69.57		B5DFF9_RAT (1-424): 4.52e-171: 494: 42.49
+	Ce
		939151 SUMO_CAEEL (1-88): 4.84e-33: 111: 47.78		GEI17_CAEEL (129-518): 4.85e-92: 299: 30.65
+	At
		1228125 SUMO2_ARATH (3-89): 1.47e-37: 123: 49.43		SIZ1_ARATH (5-518): 5.56e-67: 234: 19.66
+	At
		939035 SUMO1_ARATH (3-86): 1.07e-34: 115: 50.00		SIZ1_ARATH (5-518): 5.56e-67: 234: 19.66
+	At
		1228124 SUMO3_ARATH (3-88): 1.56e-32: 110: 43.18		SIZ1_ARATH (5-518): 5.56e-67: 234: 19.66
+	Rn
		93350 SUMO3_RAT (1-88): 3.42e-37: 122: 69.57		D4AE97_RAT (59-435): 2.71e-58: 210: 21.28
+	Hs
		964378 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		ZMIZ2_HUMAN (79-427): 1.51e-58: 210: 22.25