HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: INAR1 (P17181)
Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1)
Gene: IFNAR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39499777
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043235 - receptor complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 557
+	Hs
		410597 ERBB2_HUMAN (5-1203): 0: 1119: 48.38		INAR1_HUMAN (1-557): 1.73e-149: 442: 100.00
+	Hs
		362852 EGFR_HUMAN (1-1210): 0: 1246: 100.00		L1CAM_HUMAN (6-535): 2.49e-43: 168: 10.35
+	Hs
		362658 EGFR_HUMAN (1-1210): 0: 1246: 100.00		PTPRF_HUMAN (99-540): 1.81e-25: 113: 11.31
+	Hs
		362779 EGFR_HUMAN (1-1210): 0: 1246: 100.00		PTPRD_HUMAN (99-452): 1.68e-23: 107: 14.68
+	Hs
		362899 EGFR_HUMAN (1-1210): 0: 1246: 100.00		IL6RB_HUMAN (29-444): 3.06e-22: 103: 10.76
+	Hs
		363225 EGFR_HUMAN (1-1210): 0: 1246: 100.00		PTPRS_HUMAN (99-440): 2.43e-22: 103: 13.22
+	Rn
		1052136 Q8K3F9_RAT (5-1203): 0: 1135: 48.97		L1CAM_RAT (6-535): 6.94e-52: 193: 10.91
+	Hs
		363641 EGFR_HUMAN (1-1210): 0: 1246: 100.00		TITIN_HUMAN (27-125): 9.34e-10: 64.2: 12.50
+	Hs
		410658 ERBB2_HUMAN (5-1203): 0: 1119: 48.38		L1CAM_HUMAN (6-535): 2.49e-43: 168: 10.35
+	Rn
		1052135 ERBB3_RAT (1-1205): 0: 1092: 40.96		L1CAM_RAT (6-535): 6.94e-52: 193: 10.91
+	Hs
		641500 ERBB3_HUMAN (1-1205): 0: 1102: 41.39		L1CAM_HUMAN (6-535): 2.49e-43: 168: 10.35
+	Hs
		410579 ERBB2_HUMAN (5-1203): 0: 1119: 48.38		INGR1_HUMAN (225-542): 2.41e-30: 126: 16.19
+	Hs
		410550 ERBB2_HUMAN (5-1203): 0: 1119: 48.38		PTPRF_HUMAN (99-540): 1.81e-25: 113: 11.31
+	Hs
		410678 ERBB2_HUMAN (5-1203): 0: 1119: 48.38		IL6RB_HUMAN (29-444): 3.06e-22: 103: 10.76
+	Hs
		410813 ERBB2_HUMAN (5-1203): 0: 1119: 48.38		PTPRS_HUMAN (99-440): 2.43e-22: 103: 13.22
+	Hs
		641504 ERBB3_HUMAN (1-1205): 0: 1102: 41.39		IL6RB_HUMAN (29-444): 3.06e-22: 103: 10.76
+	Hs
		410975 ERBB2_HUMAN (5-1203): 0: 1119: 48.38		SORL_HUMAN (233-455): 1.36e-12: 73: 15.22
+	Hs
		641643 ERBB3_HUMAN (1-1205): 0: 1102: 41.39		SORL_HUMAN (233-455): 1.36e-12: 73: 15.22
+	Hs
		463885 RET_HUMAN (412-1058): 7.91e-132: 433: 23.02		PTPRF_HUMAN (99-540): 1.81e-25: 113: 11.31
+	Dm
		55063 Q0KIF4_DROME (621-1017): 1.11e-113: 382: 32.07		A1Z921_DROME (21-430): 6.13e-35: 142: 14.45