Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: ITA4 (P13612)
Integrin alpha-4 (CD49 antigen-like family member D) (Integrin alpha-IV) (VLA-4 subunit alpha) (CD antigen CD49d)
Gene: ITGA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 19738201
Identification Methods affinity chromatography technology, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007160 - cell-matrix adhesion
GO:0007229 - integrin-mediated signaling pathway
GO:0034446 - substrate adhesion-dependent cell spreading
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 2477
Hs

1 1032
+ Hs
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Last updated: 15 Jul 2024