Interactor 1: CXL10 (P02778)
C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) [Cleaved into: CXCL10(1-73)]
Gene: CXCL10

Interactor 2: PF4V (P10720)
Platelet factor 4 variant (C-X-C motif chemokine 4 variant) (CXCL4L1) (PF4alt) (PF4var1) [Cleaved into: Platelet factor 4 variant(4-74); Platelet factor 4 variant(5-74); Platelet factor 4 variant(6-74)]
Gene: PF4V1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 28381538
Identification Methods pull down, filter binding
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:0008009 - chemokine activity
GO:0008201 - heparin binding
GO:0030593 - neutrophil chemotaxis
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 98
Hs

1 104
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Last updated: 15 Jul 2024