HitPredict

Interactor 1: CXL10 (P02778)
C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) [Cleaved into: CXCL10(1-73)]
Gene: CXCL10

Interactor 2: IRF2 (P14316)
Interferon regulatory factor 2 (IRF-2)
Gene: IRF2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17167270
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 349
+	Mm
		621185 CXL11_MOUSE (1-96): 7.43e-24: 88.6: 31.25		IRF2_MOUSE (1-349): 0: 525: 92.55
+	Hs
		150309 CXL11_HUMAN (1-94): 7.39e-27: 95.9: 30.85		IRF2_HUMAN (1-349): 0: 511: 100.00
+	Hs
		364096 CXL10_HUMAN (1-98): 4.33e-29: 101: 100.00		IRF1_HUMAN (1-265): 1.74e-104: 311: 46.69
+	Hs
		150307 CXL11_HUMAN (1-94): 7.39e-27: 95.9: 30.85		IRF1_HUMAN (1-265): 1.74e-104: 311: 46.69
+	Hs
		486172 IL8_HUMAN (14-92): 7.33e-23: 86.3: 23.17		IRF1_HUMAN (1-265): 1.74e-104: 311: 46.69
+	Hs
		364111 CXL10_HUMAN (1-98): 4.33e-29: 101: 100.00		IRF9_HUMAN (7-231): 1.48e-73: 234: 27.19
+	Mm
		576101 CXCL9_MOUSE (1-90): 3.44e-27: 97.8: 35.56		IRF8_MOUSE (7-215): 2.85e-60: 201: 30.14
+	Hs
		364114 CXL10_HUMAN (1-98): 4.33e-29: 101: 100.00		IRF3_HUMAN (1-211): 4.16e-52: 180: 24.54
+	Hs
		486202 IL8_HUMAN (14-92): 7.33e-23: 86.3: 23.17		IRF3_HUMAN (1-211): 4.16e-52: 180: 24.54
+	Hs
		364117 CXL10_HUMAN (1-98): 4.33e-29: 101: 100.00		IRF7_HUMAN (4-111): 1.03e-38: 145: 32.48