HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: SEM4B (Q62179)
Semaphorin-4B (Semaphorin-C) (Sema C)
Gene: Sema4b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 259 Mm			1 823
+	Mm
		139664 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SEM3A_MOUSE (13-707): 0: 699: 29.18
+	Hs
		420743 KLK1_HUMAN (5-257): 1.35e-96: 285: 33.21		SEM3B_HUMAN (1-752): 0: 651: 29.91
+	Mm
		292031 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SEM3F_MOUSE (16-667): 0: 593: 27.79
+	Hs
		1271968 KLK6_HUMAN (1-255): 6.18e-98: 288: 32.69		SEM4G_HUMAN (9-660): 0: 615: 37.54
+	Hs
		320776 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		SEM4F_HUMAN (3-658): 0: 582: 36.43
+	Mm
		222742 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SEM6B_MOUSE (30-564): 1.21e-166: 507: 32.46
+	Mm
		372643 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SEM7A_MOUSE (2-688): 7.61e-160: 482: 26.05
+	Hs
		177847 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		PLXA3_HUMAN (42-752): 2.87e-155: 499: 17.69
+	Hs
		850504 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		PLXA3_HUMAN (42-752): 2.87e-155: 499: 17.69
+	Hs
		1329620 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		SEM6B_HUMAN (30-564): 1.93e-165: 504: 32.16
+	Mm
		371769 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		PLXA1_MOUSE (5-797): 3.58e-145: 472: 19.11
+	Hs
		1198167 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		SEM6A_HUMAN (13-568): 8.57e-158: 488: 29.34
+	Hs
		1329263 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		SEM6A_HUMAN (13-568): 8.57e-158: 488: 29.34
+	Hs
		1345087 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		PLXA1_HUMAN (4-797): 1.61e-148: 481: 19.20
+	Hs
		1329636 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		PLXA1_HUMAN (4-797): 1.61e-148: 481: 19.20
+	Hs
		426543 KLK3_HUMAN (25-256): 3.03e-37: 133: 35.37		SEM4G_HUMAN (9-660): 0: 615: 37.54
+	Hs
		426541 KLK3_HUMAN (25-256): 3.03e-37: 133: 35.37		SEM6B_HUMAN (30-564): 1.93e-165: 504: 32.16
+	Hs
		426515 KLK3_HUMAN (25-256): 3.03e-37: 133: 35.37		PLXA3_HUMAN (42-752): 2.87e-155: 499: 17.69