HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30415952, 36424410, 25452129
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005819 - spindle GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 2240
+	Hs
		406577 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		DIDO1_HUMAN (1-2240): 0: 727: 100.00
+	Hs
		372922 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MINT_HUMAN (64-2011): 7.02e-52: 205: 9.54
+	Hs
		371474 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		YLPM1_HUMAN (1428-2236): 9.22e-43: 175: 14.56
+	Hs
		371886 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		BPTF_HUMAN (82-420): 1.92e-38: 161: 14.29
+	Hs
		373368 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		CHD7_HUMAN (1473-1965): 9.84e-37: 155: 13.64
+	Hs
		373360 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		CXXC1_HUMAN (245-393): 1.67e-34: 144: 26.75
+	Hs
		373506 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PHF8_HUMAN (236-386): 5.95e-24: 112: 23.31
+	Hs
		373111 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		NSRP1_HUMAN (2033-2240): 1.1e-23: 110: 18.27
+	Hs
		372705 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		TITIN_HUMAN (2-1275): 9.47e-22: 106: 10.12
+	Hs
		372716 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PHF3_HUMAN (1933-2219): 8.09e-18: 93.2: 20.19
+	Hs
		371554 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SC24C_HUMAN (1537-1898): 1.68e-16: 88.6: 19.74
+	Hs
		274070 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ANR17_HUMAN (1543-2076): 6.28e-14: 80.5: 13.59
+	Hs
		373517 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SRRM2_HUMAN (1059-2186): 1.18e-12: 76: 8.75
+	Hs
		370960 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		CO1A2_HUMAN (1678-2167): 7.77e-11: 69.9: 12.17
+	Hs
		372739 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		CBP_HUMAN (1049-1978): 2.17e-09: 65.4: 9.35
+	Hs
		372001 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		EIF3A_HUMAN (1921-2141): 4.61e-09: 64.3: 12.65
+	Hs
		406440 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		TITIN_HUMAN (2-1275): 9.47e-22: 106: 10.12
+	Hs
		406447 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		PHF3_HUMAN (1933-2219): 8.09e-18: 93.2: 20.19
+	Hs
		405937 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		SC24C_HUMAN (1537-1898): 1.68e-16: 88.6: 19.74
+	Hs
		274074 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		ANR17_HUMAN (1543-2076): 6.28e-14: 80.5: 13.59