Protein: NSRP1
Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70)

Gene: NSRP1
Organism: Homo sapiens
Interactions: 166
UniProt ID: Q9H0G5

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001701 - in utero embryonic development
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1356402

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

3

1

High-throughput

0.656

High

1239663

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

3

0

Small-scale

0.638

High

1006698

SRPK2
SRSF protein kinase 2

2

6

High-throughput

0.634

High

1371680

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

5

Small-scale

0.611

High

905124

MECP2
Methyl-CpG-binding protein 2

2

4

High-throughput

0.584

High

998790

H31
Histone H3.1

2

7

High-throughput

0.584

High

1402570

SRPK1
SRSF protein kinase 1

1

4

High-throughput

0.550

High

1242424

RHGBA
Rho GTPase-activating protein 11A

2

0

High-throughput

0.547

High

1400012

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

3

High-throughput

0.536

High

123826

MYO1C
Unconventional myosin-Ic

1

3

High-throughput

0.536

High

164085

NDC80
Kinetochore protein NDC80 homolog

1

3

High-throughput

0.536

High

251652

CCNT1
Cyclin-T1

1

1

High-throughput

0.536

High

286070

SF3B1
Splicing factor 3B subunit 1

1

1

High-throughput

0.536

High

471920

RU2B
U2 small nuclear ribonucleoprotein B''

1

4

High-throughput

0.536

High

478204

SNRPA
U1 small nuclear ribonucleoprotein A

1

4

High-throughput

0.536

High

659298

SP100
Nuclear autoantigen Sp-100

1

8

High-throughput

0.536

High

1023615

CYC
Cytochrome c

1

2

High-throughput

0.536

High

1057659

CDK18
Cyclin-dependent kinase 18

1

3

High-throughput

0.536

High

1117665

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.536

High

1149189

SF3A1
Splicing factor 3A subunit 1

1

2

High-throughput

0.536

High

1368799

EZH1
Histone-lysine N-methyltransferase EZH1

1

1

High-throughput

0.536

High

1370106

RENT1
Regulator of nonsense transcripts 1

1

1

High-throughput

0.536

High

1411704

RIOK1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.536

High

1415625

RIOK2
Serine/threonine-protein kinase RIO2

1

2

High-throughput

0.536

High

1429456

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

1

High-throughput

0.536

High

1430022

RBM12
RNA-binding protein 12

1

8

High-throughput

0.536

High

1430036

TPX2
Targeting protein for Xklp2

1

3

High-throughput

0.536

High

1402295

RANB9
Ran-binding protein 9

1

1

Small-scale

0.527

High

220015

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

480306

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

570975

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

948586

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1016375

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

1105410

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.513

High

861772

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

High-throughput

0.501

High

1349761

FBX25
F-box only protein 25

1

1

Small-scale

0.501

High

1093772

GAGE5
G antigen 5

1

1

High-throughput

0.489

High

1136355

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.489

High

1196246

GAG2E
G antigen 2E

1

1

High-throughput

0.489

High

1242043

SCYL2
SCY1-like protein 2

1

2

High-throughput

0.489

High

1430017

SLK
STE20-like serine/threonine-protein kinase

1

3

High-throughput

0.489

High

1430032

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

1

High-throughput

0.489

High

1430034

ANR50
Ankyrin repeat domain-containing protein 50

1

3

High-throughput

0.489

High

1361524

CTBL1
Beta-catenin-like protein 1

1

0

High-throughput

0.486

High

129802

CBX4
E3 SUMO-protein ligase CBX4

1

6

High-throughput

0.479

High

212326

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

2

High-throughput

0.479

High

217517

E41L2
Band 4.1-like protein 2

1

3

High-throughput

0.479

High

252265

CCNT2
Cyclin-T2

1

1

High-throughput

0.479

High

280816

PR40A
Pre-mRNA-processing factor 40 homolog A

1

5

High-throughput

0.479

High

318535

TOX4
TOX high mobility group box family member 4

1

7

High-throughput

0.479

High

373111

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.479

High

406628

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

461918

HS90A
Heat shock protein HSP 90-alpha

1

5

High-throughput

0.479

High

476813

RSSA
Small ribosomal subunit protein uS2

1

2

High-throughput

0.479

High

542212

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.479

High

589643

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

636146

CD11B
Cyclin-dependent kinase 11B

1

3

High-throughput

0.479

High

684385

DDX6
Probable ATP-dependent RNA helicase DDX6

1

3

High-throughput

0.479

High

696458

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

877225

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.479

High

889196

RBM25
RNA-binding protein 25

1

9

High-throughput

0.479

High

897969

CDK9
Cyclin-dependent kinase 9

1

3

High-throughput

0.479

High

935625

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.479

High

971060

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

981082

H2B1C
Histone H2B type 1-C/E/F/G/I

1

12

High-throughput

0.479

High

1005081

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

1083435

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

1

High-throughput

0.479

High

1097551

CBX3
Chromobox protein homolog 3

1

6

High-throughput

0.479

High

1109212

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

5

High-throughput

0.479

High

1127153

RBM39
RNA-binding protein 39

1

5

High-throughput

0.479

High

1128111

DHX8
ATP-dependent RNA helicase DHX8

1

4

High-throughput

0.479

High

1130447

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

High-throughput

0.479

High

1135530

RHG19
Rho GTPase-activating protein 19

1

3

High-throughput

0.479

High

1138037

TNIP1
TNFAIP3-interacting protein 1

1

11

High-throughput

0.479

High

1140829

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

1144463

NONO
Non-POU domain-containing octamer-binding protein

1

4

High-throughput

0.479

High

1148560

SF3B4
Splicing factor 3B subunit 4

1

2

High-throughput

0.479

High

1160288

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

4

High-throughput

0.479

High

1205097

FA76B
Protein FAM76B

1

1

High-throughput

0.479

High

1241292

TAF2
Transcription initiation factor TFIID subunit 2

1

1

High-throughput

0.479

High

1248077

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

1

High-throughput

0.479

High

1250040

WDR82
WD repeat-containing protein 82

1

9

High-throughput

0.479

High

1271853

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.479

High

1276768

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1289615

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1294116

DDX42
ATP-dependent RNA helicase DDX42

1

1

High-throughput

0.479

High

1311854

DHX40
Probable ATP-dependent RNA helicase DHX40

1

4

High-throughput

0.479

High

1313422

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

1329104

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

4

High-throughput

0.479

High

1336755

RB15B
Putative RNA-binding protein 15B

1

2

High-throughput

0.479

High

1346925

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

1347756

FA76A
Protein FAM76A

1

1

High-throughput

0.479

High

1359598

ATX2L
Ataxin-2-like protein

1

1

High-throughput

0.479

High

1360475

PSPC1
Paraspeckle component 1

1

4

High-throughput

0.479

High

1368376

REQU
Zinc finger protein ubi-d4

1

6

High-throughput

0.479

High

1380152

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.479

High

1406772

BARD1
BRCA1-associated RING domain protein 1

1

6

High-throughput

0.479

High

1414560

DDX23
Probable ATP-dependent RNA helicase DDX23

1

4

High-throughput

0.479

High

1419686

GTPB4
GTP-binding protein 4

1

1

High-throughput

0.479

High

1430020

ECT2
Protein ECT2

1

4

High-throughput

0.479

High

1430024

DCA13
DDB1- and CUL4-associated factor 13

1

4

High-throughput

0.479

High

1430025

DJC17
DnaJ homolog subfamily C member 17

1

4

High-throughput

0.479

High

1430027

DDX56
Probable ATP-dependent RNA helicase DDX56

1

6

High-throughput

0.479

High

1430028

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

1430031

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1430033

XPO7
Exportin-7

1

1

High-throughput

0.479

High

1430035

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

3

High-throughput

0.479

High

228366

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

573245

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

634883

HXA5
Homeobox protein Hox-A5

1

0

High-throughput

0.458

High

675671

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

703057

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.458

High

809837

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

872022

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.458

High

967959

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.458

High

978716

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

992648

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

1012255

RT11
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.458

High

1116297

PTC1
Protein patched homolog 1

1

0

Small-scale

0.458

High

1277930

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1332844

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.458

High

1335318

FA98A
Protein FAM98A

1

0

High-throughput

0.458

High

1400694

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.458

High

1405376

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1412427

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1413975

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

1430019

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1430030

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

0

High-throughput

0.458

High

1430037

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.458

High

1430038

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

423126

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.457

High

638885

CNR1
Cannabinoid receptor 1

1

1

Small-scale

0.457

High

213371

ARHG9
Rho guanine nucleotide exchange factor 9

1

1

High-throughput

0.437

High

302951

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.437

High

320590

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

4

High-throughput

0.437

High

995810

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.437

High

1135097

CUL7
Cullin-7

1

3

High-throughput

0.437

High

1227428

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.437

High

1246978

RICTR
Rapamycin-insensitive companion of mTOR

1

2

High-throughput

0.437

High

1326800

ARG39
Rho guanine nucleotide exchange factor 39

1

4

High-throughput

0.437

High

1363399

STAR8
StAR-related lipid transfer protein 8

1

2

High-throughput

0.437

High

1393343

DOCK6
Dedicator of cytokinesis protein 6

1

1

High-throughput

0.437

High

1419476

DOCK9
Dedicator of cytokinesis protein 9

1

1

High-throughput

0.437

High

1430018

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.437

High

1430026

TBA8
Tubulin alpha-8 chain

1

4

High-throughput

0.437

High

1430039

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

3

High-throughput

0.437

High

1064025

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.407

High

169209

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

184911

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.279

Low

488080

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

1013336

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

1218122

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1326898

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.279

Low

1384723

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1392167

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1430023

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.279

Low

1430029

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

1390390

CNRP1
CB1 cannabinoid receptor-interacting protein 1

1

0

Small-scale

0.275

Low

608350

EGLN
Endoglin

1

0

High-throughput

0.261

Low

1430021

DISC1
Disrupted in schizophrenia 1 protein

1

0

Small-scale

0.261

Low

359735

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.249

Low

720532

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low

1051313

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.249

Low

1124716

SRC8
Src substrate cortactin

1

0

High-throughput

0.249

Low

1178729

MGAL
Probable maltase-glucoamylase 2

1

0

High-throughput

0.249

Low

1213083

RHG21
Rho GTPase-activating protein 21

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025