HitPredict

Interactor 1: IFNB (P01574)
Interferon beta (IFN-beta) (Fibroblast interferon)
Gene: IFNB1

Interactor 2: IRF8 (Q02556)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
Gene: IRF8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9092512
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 187 Hs			1 426
+	Mm
		378382 IFNB_MOUSE (1-187): 4.51e-60: 186: 49.20		IRF8_MOUSE (1-426): 0: 579: 89.67
+	Hs
		378376 IFNB_HUMAN (1-187): 1.54e-76: 228: 100.00		IRF5_HUMAN (9-414): 5.25e-156: 451: 30.36
+	Hs
		378235 IFNA1_HUMAN (10-186): 1.83e-74: 223: 31.49		IRF5_HUMAN (9-414): 5.25e-156: 451: 30.36
+	Hs
		378331 IFN14_HUMAN (10-186): 1.72e-71: 216: 32.60		IRF5_HUMAN (9-414): 5.25e-156: 451: 30.36
+	Mm
		378385 IFNB_MOUSE (1-187): 4.51e-60: 186: 49.20		IRF5_MOUSE (9-424): 7.62e-159: 459: 31.00
+	Hs
		378377 IFNB_HUMAN (1-187): 1.54e-76: 228: 100.00		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		378237 IFNA1_HUMAN (10-186): 1.83e-74: 223: 31.49		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		378252 IFNA2_HUMAN (23-187): 2.09e-72: 218: 33.73		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		378271 IFNA7_HUMAN (9-186): 3.81e-72: 218: 32.62		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		378333 IFN14_HUMAN (10-186): 1.72e-71: 216: 32.60		IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68
+	Hs
		378379 IFNB_HUMAN (1-187): 1.54e-76: 228: 100.00		IRF7_HUMAN (12-385): 3.08e-114: 345: 21.91
+	Hs
		378240 IFNA1_HUMAN (10-186): 1.83e-74: 223: 31.49		IRF7_HUMAN (12-385): 3.08e-114: 345: 21.91
+	Hs
		378257 IFNA2_HUMAN (23-187): 2.09e-72: 218: 33.73		IRF7_HUMAN (12-385): 3.08e-114: 345: 21.91
+	Hs
		378274 IFNA7_HUMAN (9-186): 3.81e-72: 218: 32.62		IRF7_HUMAN (12-385): 3.08e-114: 345: 21.91
+	Hs
		378340 IFN14_HUMAN (10-186): 1.72e-71: 216: 32.60		IRF7_HUMAN (12-385): 3.08e-114: 345: 21.91
+	Hs
		378355 IFNB_HUMAN (1-187): 1.54e-76: 228: 100.00		IRF1_HUMAN (9-187): 2.61e-62: 206: 33.69
+	Hs
		378227 IFNA1_HUMAN (10-186): 1.83e-74: 223: 31.49		IRF1_HUMAN (9-187): 2.61e-62: 206: 33.69
+	Hs
		378248 IFNA2_HUMAN (23-187): 2.09e-72: 218: 33.73		IRF1_HUMAN (9-187): 2.61e-62: 206: 33.69
+	Hs
		378326 IFN14_HUMAN (10-186): 1.72e-71: 216: 32.60		IRF1_HUMAN (9-187): 2.61e-62: 206: 33.69
+	Hs
		378356 IFNB_HUMAN (1-187): 1.54e-76: 228: 100.00		IRF2_HUMAN (9-167): 4.71e-53: 182: 36.88