HitPredict

Interactor 1: IFNB (P01575)
Interferon beta (IFN-beta)
Gene: Ifnb1

Interactor 2: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17702615, 21731497
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042742 - defense response to bacterium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 182 Mm			1 424
+	Mm
		456561 IFNA4_MOUSE (6-180): 7.77e-70: 211: 21.35		IRF8_MOUSE (1-424): 0: 586: 100.00
+	Hs
		378372 IFNB_HUMAN (1-182): 2.32e-66: 202: 49.20		IRF8_HUMAN (1-424): 0: 574: 89.67
+	Hs
		378235 IFNA1_HUMAN (6-181): 3.81e-87: 255: 24.58		IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75
+	Hs
		378331 IFN14_HUMAN (6-181): 1.29e-85: 251: 27.37		IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75
+	Mm
		456562 IFNA4_MOUSE (6-180): 7.77e-70: 211: 21.35		IRF5_MOUSE (9-422): 1.82e-165: 476: 33.04
+	Hs
		378237 IFNA1_HUMAN (6-181): 3.81e-87: 255: 24.58		IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72
+	Hs
		378252 IFNA2_HUMAN (13-182): 2.64e-86: 253: 26.74		IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72
+	Hs
		378333 IFN14_HUMAN (6-181): 1.29e-85: 251: 27.37		IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72
+	Hs
		378271 IFNA7_HUMAN (6-181): 5.03e-85: 250: 24.58		IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72
+	Mm
		456564 IFNA4_MOUSE (6-180): 7.77e-70: 211: 21.35		IRF3_MOUSE (9-396): 7.47e-136: 397: 24.69
+	Hs
		378240 IFNA1_HUMAN (6-181): 3.81e-87: 255: 24.58		IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46
+	Hs
		378257 IFNA2_HUMAN (13-182): 2.64e-86: 253: 26.74		IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46
+	Hs
		378340 IFN14_HUMAN (6-181): 1.29e-85: 251: 27.37		IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46
+	Hs
		378274 IFNA7_HUMAN (6-181): 5.03e-85: 250: 24.58		IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46
+	Mm
		456563 IFNA4_MOUSE (6-180): 7.77e-70: 211: 21.35		IRF7_MOUSE (1-383): 5.56e-120: 358: 25.11
+	Hs
		378227 IFNA1_HUMAN (6-181): 3.81e-87: 255: 24.58		IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27
+	Hs
		378248 IFNA2_HUMAN (13-182): 2.64e-86: 253: 26.74		IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27
+	Hs
		378326 IFN14_HUMAN (6-181): 1.29e-85: 251: 27.37		IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27
+	Hs
		378355 IFNB_HUMAN (1-182): 2.32e-66: 202: 49.20		IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27
+	Hs
		378356 IFNB_HUMAN (1-182): 2.32e-66: 202: 49.20		IRF2_HUMAN (9-167): 5.96e-59: 197: 37.50